IMMS Flashcards

(62 cards)

1
Q

Wilson’s disease is a type of genetic disorder affecting the active transport in the body. What is the Na+/K+ ATPase an example of

A

Tbc

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2
Q

What does a diamond represent on a genetic pedigree chart

A

Undetermined gender in a pregnancy

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3
Q

Proteins often have multiple levels of folding. An alpha helix is an example of what kind of protein structure

A

Secondary

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4
Q

A reproductive union between 2 relatives is the definition for

A

Consanguinity

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5
Q

Some types of chemotherapy inhibit the enzyme topoisomerase. What is the function of topoisomerase

A

Unwinds the DNA double helix by relieving the supercoil

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6
Q

The amount of glucose within a cell has to be closely regulated and controlled. What is the rate-limiting enzyme of glycolysis

A

Phosphofructokinase-1

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7
Q

Enolase converts which substrate into phosphoenolpyruvate in glycolysis, what does an enolase enzyme generally do

A

Tbc

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8
Q

Where does the krebs cycle take place

A

Tbc

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9
Q

Which enzyme is involved in the production of FADH2 in the krebs cycle

A

Tbc

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10
Q

Some cells have very distinctive features that can easily be identified in a histological slide; in which cell are you most likely to find a perinuclear huff

A

A plasma cell

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11
Q

Many blood borne cells have to be regulated to ensure there are adequate amounts present in the blood. What is the regulatory hormone for platelets

A

Tbc

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12
Q

Which cell type has a reniform nucleus (histology)

A

Monocyte

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13
Q

A woman is brought to A&E by an ambulance following a myocardial infarction. After a series of tests, it is found that her atrioventricular node has suffered an infarction. Which artery is the main supply to the atrioventricular node (AVN)

A

Tbc

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14
Q

In a foetus various arteries arise as branches of the pharyngeal arch, which arch does the maxillary artery arise from

A

Arch 1

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15
Q

Give 2 vasodilators

A

Prostacyclin
Atrial natuiretic peptide (ANP)
Bradykinin
Nitrous oxide

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16
Q

Give 2 vasoconstrictors

A

Angiotensin II

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17
Q

In a myocardial action potential, what happens at phase 2

A

Tbc

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18
Q

What does the T wave represent on an ECG

A

TBC

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19
Q

What is contained within the dense granules of platelets

A

Tbc

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20
Q

What does the bulbus cordis develop into

A

Tbc

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21
Q

Respiratory epithelium is found in many parts of the respiratory tract except

A

The larynx

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22
Q

What is the function of the pericilliary fluid

A

Tbc

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23
Q

A patient develops a lung carcinoma at the carina. At which level of the thoracic vertebrae does the trachea bifurcate

A

T4

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24
Q

What is the definition of functional plasticity?

A

Tbc

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25
There are many tests that are very useful to help diagnose respiratory diseases. What is the purpose of exhaled nitric oxide test
Tbc
26
Where can you find central chemoreceptors
Tbc
27
What percentage of the surface area of an alveoli does type 1 pneumocyte usually make up
Tbc
28
The diaphragm receives motor innervation from which nerve
Phrenic nerve
29
Which cartilages are attached to the vocal cords
Tbc
30
At which thoracic vertebral level does the hiatus for the inferior vena cava lie
T8
31
Give an example of mucosa-associated lymphoid tissue
Tbc
32
Give 4 components of saliva
Tbc
33
Give some salivary glands which give purely serous secretions
Parotid gland | Von Ebners gland
34
Give 2 factors that increase the strength of gastric peristaltic contractions
Gastrin | Gastric distention
35
Give all of the fat soluble vitamins
Vitamin A, D, E and K
36
Which cell is equivalent of a pacemaker cell in the intestines
Interstitial cells of cajal
37
What BMI range is considered to be overweight
Tbc
38
What BMI range is considered to be obese
Tbc
39
What BMI range is considered to be severely obese
Tbc
40
Fluid is absorbed in the gastrointestinal tract by the small intestine. What percentage of fluid is absorbed in the small intestine
Tbc
41
Which hormone is the main hormone stimulating bile secretion
Cholecystokinin
42
Hyponatraemia is a lack of which ion
Sodium
43
What is the typical fluid volume distribution in the interstitial compartment and intracellular compartment in a 70kg male
Interstitial | Intracellular
44
Syndrome of inappropriate antidiuretic hormone (SIADH) has a genetic component to it. What is a method of genetic testing in pregnancy?
Tbc
45
Define penetrance in genetics
Tbc
46
Where does haematopoiesis occur in a foetus
Tbc
47
Where does haematopoiesis occur in an adult
Tbc
48
Give the structure of foetal haemoglobin
Tbc
49
Give the structure of adult haemoglobin
2 alpha chains | 2 beta chains
50
A woman who gives birth at a hospital suffers severe blood loss asa result of postpartum haemorrhage. Why does the haematocrit not changefolloing a major trauma in which a lot of blood is lost
Tbc
51
Define FEV1
Tbc
52
Define FVC
TBC
53
Name a method that can be used to measure total lung capacity
Tbc
54
FVC below 80% of predicted value is indicative of?
Tbc
55
State 2 effects of ageing on lung function
Tbc
56
What type of prevention i smoking cessation in regards to lung cancer
Tbc
57
What is pernicious anaemia
Pernicious anaemia is an autoimmune disease affecting the parietal cells of the stomach
58
Where in the stomach are you most likely to find G cells (enteroendocrine cells)
Tbc
59
Give two vitamins absorbed in the terminal ileum
Vitamin B12
60
Give 4 features used to distinguish the small intestine from the colon
Colon - peripheral location - epiploic appendices - haustrations - taenia coli Small intestine - central location - plicae circularis - villi - microvilli
61
Define Sensitivity
Tbc
62
Define specificity
Tbc