IHD & Heart Failure Flashcards
If a person with chest pain does not require immediate admission or referal what investigations should you consider & why?
- ECG: check for abnormalities
- Blood glucose: risk factor
- Lipids: risk factor
- U&Es: CKD is risk factor
- FBC: check for anaemia which may be precpitating angina
- TFTs: hyperthyroidism may precipitating angina
- LFTs: check for cholecystitis as cuase of chest pain
- Amylase: pancreatitis as cause of chest pain
- CRP & ESR: infection as cause
- CXR: check for pulmonary pathology or heart failure
State some risk factors for CVD, include:
- Modifiable
- Non-modifiable
- Comorbidities that increase risk
Risk factors
- Non-modifiable:
- Age
- Gender- male
- Family history
- Ethnic background (south asian, sub-saharan african)
- Modifiable:
- Smoking
- High non-HDL cholesterol
- Low HDL cholesterol
- Sedentary lifestyle
- Alcohol intake
- Obesity
- Unhealth diet
- Comorbidities:
- Hypertension
- Diabetes
- CKD
- AF
- RA, SLE, systemic inflammatroy disorders
- Serious mentalhealth disorders
Discuss the presentation of angina- include typical and atypical angina
- Typical angina presents with all of the following:
- Precipitated by physical exertion
- Constricting discomfortin the front of chest, neck, shoulders, jaw or arms
- Relieved by rest or GTN within about 5 minutes
- Atypical angina presents with two of the above features
- Additional symptoms may include GI discomfort/nausea& vomitting, breathlessness, sweating etc..
What investigations would you do in primary care if you suspect stable angina?
Where do you refer them to for further investigations?
What information & treatment may you give whilst awating results from diagnnostic testing?
- Do ECG to rule out any myocardial ischaemia at present or previous infarction
- Check for risk factors/comorbidities:
- BMI
- BP
- Lipids
- HbA1c
- If person has typical or atypical angina pain refer to specialist chest pain service to confirm or exlcude the diagnosis of angina.
- Prescribe sublingual GTN and consider aspirin 75mg. Provide safety netting advice
Discuss the managment of stable angina, include:
- Conservative
- Pharmacological
Conservative
- Explain diagnosis, long term course of angina & educate on factors that can provoke angina e.g. exertion, emotional stress, cold, large meal
- Lifestyle changes: stop smoking, reduce alcohol, weight loss, increase physical activity
- If take PDEi for ED advise must not take GTN for at least 24hrs after last dose of PDEi. If have angina attack must call 999 and not use GTN
- Saftey net: seek medical help if sudden worsening or increase in frequency
Pharmacological
- ALL- GTN (sublingual glyceryl trinitrate)
- ALL- asprin 75mg daily CVD prevention (if already on clopidogrel for stroke or PAD then leave on that)
- ALL- statin 20mg atorvastatin
- Consider ACE inhibitor in diabetics
- Beta blocker or non-dihydropyridine CCB
- Switch from BB to CCB and vice versa
- Both BB & CCB
- Consider treatment such as isosorbide monotitrate, ivabradine, nicorandil, ranolazine
**AND obviously treat any other comorbidities
When should you refer someone with stable angina to a specialist?
- Previous Mi, CABG, PCI and develop angina
- ECG shows evidence of previous MI or other significant abnormality
- Newly diagnosed AF and stableangina
- Heart failure and angina
- Any suggestions of hypertrophic cardiomyopathy
- Doubt about diagnosis
- Presence of several risk factors or strong famly history
- Doubt about diagnosis
- If person has poorly controlled angina symptoms despite treatment
*
Discuss the monitoring & follow up required for pts with stable angina
- Review response to treatment 2-4 weeks after changing or starting drug treatment
- Routine review every 6 months to 1 year depending on stability of angina & comorbidites
What should be included in a stable angina review?
- Check for ongoing symptoms- clarify when symptoms occur, have symptoms worsened
- Assess CVD risk and identify any modifiable risk factors
- Check for complications of anginaor treatment (check HR, BP, sign & symptoms of heart faillure, screen for low mood & depression)
- Review medications: adherence, symtpom control, correct use
- Re-iterate advice that should have been given: manage CVD risk, physical exertion, when to seek medical attention…
Discuss when dihydropyridine and non-dihydropyridine CCBs are used in stable angina
- If only taking CCB: rate limiting CCBs are preferred as dihydropyridines can cause reflex tachycardia which may worsen anginal symptoms
- If taking BB & CCB: prescribe a dihydropyridine as risk of heart block if take BB and rate limting/non-dihydropyridine CCB
State some risk factors for ACS- include modifiable, non-modifiable and cormorbidites that increase risk
Risk factors
- Non-modifiable:
- Age
- Gender- male
- Family history
- Ethnic background (south asian, sub-saharan african)
Modifiable:
- Smoking
- High non-HDL cholesterol
- Low HDL cholesterol
- Sedentary lifestyle
- Alcohol intake
- Obesity
- Unhealth diet
- Comorbidities:
- Hypertension
- Diabetes
- CKD
- AF
- RA, SLE, systemic inflammatroy disorders
- Serious mental health disorders
Discuss signs and symptoms of ACS
- Central, crushing chest pain
- Radiate to neck, jaw, shoulder and/or arm
- Associated sweating
- Associated nausea & vomitting
- SOB
Which pts with suspected ACS would you admit to hospital?
- Current chest pain
- Signs of complications e.g.pulmonary oedema
- Pain free but had chest pain in last 12hrs and have abnormal ECG or ECG not available
Which patients with suspected ACs would you refer for urgent same day assessment at a rapid access chest pain clinic?
- Currently pain free but had chest pain in last 12hrs and have normal ECG and no complications
- Chest pain in past 12-72hrs wtih no complications
Which patients with suspected ACS would you refer to rapid acces chest pain clinic within 2 weeks?
Currently pain free and their chest pain was more than 72hrs ago and they have no complications, suspected underlying malignancy, lung or lobar collapse or pleural effusion (basically any other suspected cause of chest pain).
*HOWEVER, as always use clinical judgement: interpreation of ECG and troponin should also guide how urgent this referrral should be
Look at Yr3 Medicine: Cardiology ACS for more info on ACS; primarily managed in secondary care intially
Remind yourself of immediate management of ACS
- Morphine
- Oxygen
- Nitrates
- Aspirin 300mg & ADP receptor antagonist
Remind yourself of management (after MONA) of:
- STEMI
- NSTEMI
- Unstable angiina
- STEMI: PCI if available within 120mins or thrombolysis if not
- NSTEMI & unstable angina: beta blocker, anticoaguation with LMWH and consider IV nitrates if pain continues
Following an MI, what medications should someone be sent home with?
- Beta blocker e.g. bisoprolol
- ACE inhibitor or ARB
- Statin
- Dual antiplatelets (aspirin 75mg and ADP receptor antagonist)
Remind yourself:
- Definition of heart failure
- Two types
- Inability of heart to maintain adequete circulation due to structural or functional impairment of ventricular filling or ejection
- Types:
- Heart failure with preserved ejection fraction (filling problem)
- Heart failure with reduced ejection fraction (contraction problem)
State some causes of heart failure highlighting the most common
- Myocardial disease
- CAD (MOST COMMON)
- Hypertension
- Cardiomyopathies
- Valvular heart disease
- Pericardial disease
- Constrictive pericarditis
- Pericardial effusion
- Arrhythmias
- High output states
- Anaemia
- Thyrotoxicosis
- Phaeochromocytoma
- Sepsis
- AV shunts
- Thiamine deficiency
- Volume overload
- CKD
- Neprhotic
- Drugs
- Alcohol
- Cocaine
State some signs & symptoms of heart failure
Symptoms
- Breathlessness: on exertion, orthopnoea, PND
- Swelling due to fluid retention
- Fatigue
- Light headedness/history of syncope
Signs
- Tachycardia
- Irregular pluse if AF present
- Laterally displaced apex beat
- Hypertension
- Raised JVP
- Hepatomegaly
- Tachypnoea
- Bibasal crepitations
- Stoney dull percussions of pleural effusions