Contraception & Sexual Health Flashcards

1
Q

GO REVISE SEM 3: REPRO CONTRACEPTION

A
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2
Q

Remind yourself of the different broad categories/forms of contraception

A
  • Abstinence
  • Barrier
  • Hormonal
  • Prevention of implantation
  • Sterilisation
  • Emergency
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3
Q

State 4 forms of ‘natural contraception’

A
  • Abstinence
  • Withdrawal
  • Fertility awareness method
  • Lactational amenorrhoea
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4
Q

State 3 forms of barrier contraception

A
  • Male condom
  • Female condom
  • Cap
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5
Q

For the male condom, discuss:

  • Mechanism of action
  • Indications
  • Contraindications
  • Important ADRs
  • Efficacy
A
  • Prevent pregnancy by providing a barrier to the ejaculate, pre-ejaculate secretions, and cervicovaginal secretions. This prevents fertilization and reduces the risk of sexually transmitted infections
  • Indications:
    • Don’t want any hormonal contraception or implanted devices
    • Protection against STIs
    • Reversible contraception/interim between alternative contraception
    • Infrequent intercourse
  • Important ADRs (not many common ones):
    • Latex allergy (can get latex free)
    • Condom splits
  • Efficacy: perfect use 98%, typical use=82%
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6
Q

Explain how to correctly use a male condom

A
  • Ensure condom packet is not damaged
  • Ensure condom is in date
  • Squeeze the teat of the condom using their forefinger and thumb to expel any air.
  • Roll the condom down the erect penis to its base before there is genital contact.
  • If the condom does not reach the base of the penis, then it is likely that the condom is inside out. The condom should be removed and replaced with a fresh one.
  • As soon as the man has ejaculated, and before the penis goes soft, the man should withdraw.
  • The condom should be removed from the penis.
  • The condom and penis should be kept away from the partner’s genital area.
  • Used condoms should be disposed of by wrapping in tissue and placing in the bin (do not flush down the toilet).
  • Should not use lubricant under condom as this may result in concom slipping off
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7
Q

Discuss whether condoms in combination with a spermicide or condoms prelubricated with a spermicide should be used

A

Not recommended because they may increase risk of transmission of blood-bourne infections such as HIV and hepatitis B or C, and there is no evidence that they provide additional protection against pregnancy.

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8
Q

Discuss advanatages & disadvantages of using male condoms

A

Advantages

  • Easy to obtain & use
  • Reduces risk of STIs
  • Effective at protecting against pregnancy if used correctly
  • Adverse effects are rare
  • Protect against cervical cancer

Disadvantages

  • Forward planning and may interrupt sex
  • The participation and commitment of both partners
  • Motivation at each act of intercourse
  • Careful disposal
  • Less effective compared to hormonal & intrauterine methods
  • Loss of sensitivity during intercourse
  • If man loses erection during intercourse may struggle to use
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9
Q

For the female condom, discuss:

  • Mechanism of action
  • Indications
  • Contraindications
  • Important ADRs
  • Efficacy
A
  • Prevent pregnancy by providing a barrier to the ejaculate, pre-ejaculate secretions, and cervicovaginal secretions; prevents fertilization and reduces the risk of sexually transmitted infections. Made of polyurethane and is pre-lubricated with dimeticone, an odourless, non-spermicidal lubricant.
  • Indications:
    • Don’t want to use hormonal contraception
    • Protect against STIs
    • Male cannot use male condom
    • Reversible contraception/interim between alternative contraception
    • Infrequent intercourse
  • Contraindications:
    • Most people can safely use; if woman not comfotable touching their gential area may be unsuitable
  • Important ADRs:
    • None
  • Efficacy: perfect use 95%, typical use 79%
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10
Q

Explain how to correctly use a female condom

A
  • Check pacakaging for any tears
  • Check for safety markings e.g. BSI & CE kite marks
  • Check in date
  • Insert condom before penis comes into contact with genitalia
  • Find a comfortable position in which to insert the condom; this may be sitting, squatting, or with one leg up on a chair.
  • Hold the closed end of the female condom and squeeze the inner ring between her thumb and middle finger. Keeping the index finger on the inner ring facilitates insertion.
  • Use her other hand to separate the labia, then put the squeezed ring into her vagina and push it up as far as it can go.
  • Place her index or middle finger, or both, inside the open end of the female condom until the inner ring can be felt, and then push the inner ring as far back into the vagina as it can go.
  • The ring will be lying just behind the pubic bone which can be felt by inserting a finger into the vagina and curving it slightly forward.
  • Following insertion, the outer ring should rest closely against the vulva.
  • Remove condom without twisting
  • Wrap in tissue & put in bin
  • Advise that is is good idea to guide penis into condom to ensure it doesn’t enter between vagina & condom
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11
Q

Discuss advantages & disadvantages of female condoms

A

Advantages

  • Reduce STI risk
  • Protect against cervical cancer
  • Can be used if either of couple is allergic to latex
  • Less likely to tear than male condoms
  • Some men prefer the ‘freer sensations’ offered by female condoms

Disadvantages

  • Motivation at each time of intercourse
  • Require careful insertion.
  • Can be dislodged, or the penis can be inserted between the vaginal wall and the female condom.
  • Can be noisy during intercourse.
  • May cause discomfort during sex due to the inner ring.
  • Are not as effective at preventing pregnancy as hormonal and intrauterine methods.
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12
Q

Discuss the mechanism of action of:

  • Diaphragms
  • Caps
A
  • Diaphragms consist of a thin, soft dome (made of latex/rubber or silicone) with an encased flexible steel ring around its edge; fit between the posterior fornix of the vagina and the pubic bone. The diaphragm is held in place by the vaginal muscles, the tension of the ring, and the pubic bone.
  • Cervical caps fit directly over the cervix and are held in place by suction and by support from the vaginal wall.
  • Both prevent semen entering the cervix and are used in combination with a spermicide to further prevent this
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13
Q

For the female condom, discuss:

  • Indications
  • Contraindications
  • Important ADRs
  • Efficacy
A
  • Indications:
    • Don’t want to use hormonal contraception
    • Want revsersible form on contraception
    • do not like feel of male or female condom
  • Contraindications:
    • Cannot be used in:
      • HIV pts or pts with high risk of HIV
      • History of toxic shock syndrome
      • Less than 6 weeks post-partum
      • Diaphragm can’t be used in vulvovaginal prolapse
      • Cap can’t be used when distorted cervical anatomy
      • Cap can’t be used if CIN or cervical cancer
  • Important ADRS:
    • _​_Repeated & high dose use of spermicide can cause vaginal & cervical irritation
  • Efficacy: perfect use= 92%, typical use 77-81%
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14
Q

Explain how to correctly use a diaphragm/cap with spermicide

A
  • Initially, should be fitted by trained professional and be used in conjunction with other methods until woman is confident can use correclty
  • Check for any holes/deterioration in diaphragm or cap
  • Apply spermicide (2 x 2cm strips for diaphragm, fill cap 1/3)
  • Insert up to 3 hrs before, leave for at least 6hrs after
  • Diaphragms must be removed after 30hrs and caps after 48hrs
  • Additional spermicide should be used if sexual intercourse is repeated or if been in situ for >3hrs before intercourse
  • After intercourse, wash cap with mild soap and water then dry
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15
Q

Discuss advantages & disadvantages of diaphragm/cap with spermicide

A

Advantages

  • They can be inserted at a convenient time (up to 3 hours) before intercourse, so that spontaneity can be maintained.
  • The woman can control the use of contraception.
  • These methods are not compromised by concurrent drug therapy

Disadvantages

  • Effectiveness is low compared with hormonal and intrauterine methods.
  • Failure rates for cervical caps (but not diaphragms) may be increased for parous women.
  • They require motivation and careful use on each occasion to be effective.
  • They require planning so that the diaphragm or cap is in place or readily available.
  • The diaphragm or cap must be left in place for at least 6 hours after sexual intercourse.
  • They cannot be used until 6 weeks post-partum or 6 weeks following second trimester termination.
  • The fit needs to be rechecked after weight gain or loss of 3 kg or more, and after giving birth.
  • Some women may be allergic to the material from which the diaphragm is made.
  • The incidence of urinary tract infection may be increased in some women who use diaphragms — this often relates to the fit and size of the diaphragm, which may put pressure on the urethra.
  • They may not reduce the risk of transmission of sexually transmitted infections (STIs).
  • They must be used with spermicide, which may cause irritation or allergy.
  • They should not be used by women at high risk of STIs, as spermicides can increase the risk of infection.
  • Some women find the method messy to use.
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16
Q

After giving a lady a cap or diaphragm you should review the devices fit & woman’s skills after 1-2 weeks; state some things you should assess at the review

A
  • Is she comfortable when using it- including during intercouse
  • Check neither her nor her partner can feel it during intercourse
  • If there are any side effects
  • Ensure she can check the position of device and recognise if incorrectly places
  • Advise that must have fit recheckedk after hildbirth, termination of pregnancy, miscarriage or if she loses >3kg
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17
Q

State some hormonal methods of contraception

A
  • Contraceptive patch
  • Combined pill
  • Progesterone only pill
  • Contraceptive vaginal ring
  • Contraceptive implant
  • Contraceptive injection
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18
Q

Discuss the contraindications for all combined oral contraceptives

*NOTE: list is big, just know main ones that are absolute contraindications.

A

Cannot give to following pts (UKMEC4):

  • Current breast cancer
  • Breastfeeding
  • <6 week post partum
  • >35yrs
  • Smokin 15 or more cigarettes/day
  • Hypertesnion >160 or >100
  • Vascular disease
  • History of stroke
  • Current or history of IHD
  • VTE
  • Known thromboembolic conditions
  • Migraine with aura

Only be used after consultation with expert (UKMEC3):

  • History of breast cancer and no evidence of recurrence for 5yrs
  • Taking liver enzyme inducing drugs e.g. rifampicin
  • BMI >35
  • Less than 15 cigarettes/day
  • Stopped smokin <1yr
  • Organ transplant with complications
  • Hypertension >140/159 or >90-99 AND also adequetely controlled
  • Immobility
  • Migraine without aura
  • Gallbladder disease
  • Liver problems
  • Diabetes with vascular disease
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19
Q

For all combined contracpetive methods discuss ADRs

A

Commonly reported:

  • Nausea
  • Abdo pain
  • Headahce
  • Breast pain/tenderness
  • Menstrual irregularities
  • Mood changes

Others/systemic:

  • Inceased risk of cardiovascular disease (small increase from 100 per 100,000 to 200 per 100,00. Greatest increase in pts with other risk factors)
  • VTE risk
  • Breast cancer
  • Cervical cancer
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20
Q

Discuss the combined hormonal contraceptive rules in regards to surgery

A

Combined hormonal contraceptives should be stopped:

  • Four weeks before any major surgery (which includes operations lasting more than 30 minute), all surgery to the legs, or surgery that involves prolonged immobilization of a lower limb.
  • If emergency surgery or immobilization (such as for a leg fracture) is necessary.

If the COC is to be stopped, advise on the use of another suitable method of contraception. The COC can be restarted 2 weeks after full mobilization.

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21
Q

For the the contraceptive patch, discuss:

  • Mechanism of action
  • Indications
  • Efficacy
A
  • Transdermal patch that releases oestrogen & progesterone- absorbd through skin into bloodstream; prevents LH and FSH production therefore preventing ovulation and thickens cervical mucus to ihibit entry of sperm
  • Indications:
    • Don’t want to use barrier contraception
    • Don’t want to take tablets
    • Don’t want device insertion
  • Efficacy: perfect use >99%, typical use 91%
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22
Q

For the contraceptive patch, describe how it should be used

A
  • Stick patch to clean, dry, hairless area of healthy skin e.g. deltoid region, upper torso, buttock, lower abdomen
  • Check patch daily to check it is still in place
  • Apply patch on same day each week for 3 consecutive weeks then have patch free interval on week 4
  • May or may not get bleeding in patch free week; bleediny may continue after patch free week but still start new cycle as planned
  • Use different site when changing patch
  • Put in bin, not toilet
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23
Q

For contraceptive patch, discuss advantages & disadvantages

A

Advantages

  • it’s very easy to use and doesn’t interrupt sex
  • you only have to remember to change it once a week
  • the hormones from the patch aren’t absorbed by the stomach, so it still works if you’re sick (vomit) or have diarrhoea
  • it can make your periods more regular, lighter and less painful
  • it can help with premenstrual symptoms
  • it may reduce the risk of ovarian, womb and bowel cancer
  • it may reduce the risk of fibroids, ovarian cysts and non-cancerous breast disease

Disadvantages

  • it may be visible
  • it can cause skin irritation, itching and soreness
  • it doesn’t protect you against STIs
  • some women get mild temporary side effects when they first start using the patch, such as headaches, sickness (nausea), breast tenderness and mood changes – this usually settles down after a few months
  • bleeding between periods (breakthrough bleeding) and spotting (very light, irregular bleeding) is common in the first few cycles of using the patch
  • you need to remember to change it every week
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24
Q

For the contraceptive patch, discuss when in the menstrual cycle it should be started

A
  • Start on day 1-5 of menstrual cycle and no additional contraception is required
  • If started any other time in cycle, contraception is required for first 7 days

***If switching from alternative contraceptive method see NICE for further guidance (if COCP, start the day after finish COCP, if POP swap at any point in cycle as long as not pregnant, if progesterone injection start before repeat is due)

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25
Q

Discuss when you would advise a woman, who has misued her patch (be this it has become detached or has used it for longer than she should) to take extra precautions

A

Only need to use emergency contraception if there has been patch detachment for 48hrs or more, or continued use of same patch for additional 48hrs or more in week 1 after hormone free interval (makes sense as ovulation happens around day 14 which is end of 1st week after HFI).

  • Advise to attach new path as soon as possible
  • Keep new patch on until scheduled removal day.
  • Use contraception for 7 days.
  • Consider follow up pregnancy test

*For all other instances, advise woman to put new patch on and change it as usual scheduled change date

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26
Q

For the contraceptive vaginal ring, discuss:

  • Mechanism of action
  • Indications
  • Contraindications
  • Important ADRs
  • Efficacy
A
  • Small, flexible plastic ring that is put into vagina & releases oestrogen & progesterone; prevents FSH and LH surge to prevent ovulation. Also thickens cervical mucus to inhibit sperm entry.
  • Indications:
    • ​Don’t want to use barrier
    • Don’t want to take pill
    • Don’t want a patch
    • Don’t want a device implanted
    • Don’t want injections
  • Contraindications: same as for all combined hormonal contraceptives
  • _Important ADRs:_same as for all combined hormonal contracpetives
  • Efficacy: perfet use >99%, typical use 91%
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27
Q

Describe how to use a contraceptive vaginal ring

A

Keep ring in for 3 weeks, then remove and have week without. Insert new one.

To insert ring:

  • Clean hands
  • Squeeze ring between thumb & index finger
  • Insert tip into vagina
  • Push ring into vagina until it feels comfortable

NOTE: ring can get lost inside you so if you can’t feel it but sure it’s there see GP or nurse

To remove ring:

  • with clean hands, put a finger into your vagina and hook it around the edge of the ring
  • gently pull the ring out
  • put it in the special bag provided and throw it in the bin
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28
Q

For the contraceptive vaginal ring, discuss when in the menstrual cycle it should be started

A
  • Insert on day 1-5 of menstrual cycle & no additional contraception is required
  • If inserted at any other time, avoid sexual intercourse or use barrier contraception for 7 days
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29
Q

Discuss advantages & disadvantages of contraceptive vaginal ring

A

Advantages:

  • it doesn’t interrupt sex
  • it’s easy to put in and take out
  • you don’t have to think about it every day or each time you have sex
  • the ring isn’t affected if you’re sick (vomit) or have diarrhoea
  • it may help with premenstrual symptoms
  • period-type bleeding usually becomes lighter, more regular and less painful

Disadvantages:

  • you may not feel comfortable inserting or removing it from your vagina
  • you can have spotting and bleeding in the first few months
  • it may cause temporary side effects, such as increased vaginal discharge, headaches, nausea, breast tenderness and mood changes
  • the ring doesn’t protect against STIs
  • you need to remember to change it and put in a new one
  • some medicines can make the ring less effective
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30
Q

Discuss when you would advise a pt to use extra precautions following mis-use of contraceptive vaginal ring (3 situations)

A

Need to use extra precautions if:

  • It has been 8 or more days since ring was removed for scheduled hormone free interval. Insert ring ASPA and take extra precautions for next 7 days. Consider ermergency contracpetin if had unprotected intercourse during or after HFI.
  • If ring is removed or expelled and left outside vagina for 48hrs or more in week 1 after HFI take extra precautions for 7 days and consider emergency contraception if unprotected sex during HFI or week 1.
  • If ring is found to be broken during use replace ASAP take extra precautions for 7 days, consider emergency contraception if UPSI taken place in previous 5 days.
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31
Q

For the combined oral contraceptive pill, discuss:

  • Mechanism of action
  • Indications
  • Contraindications
  • Important ADRs
  • Efficacy
A
  • Combination of progesterone & oestrogen; prevents FSH and LH surge to prevent ovulation. Also thickens cervical mucus to inhibit entry of sperm.
  • Indications:
    • Don’t need protection against STIs
    • Regular intercourse
    • Don’t want a device implanted/injections
  • Contraindications: same as for all combined hormonal contraceptives
  • Important ADRs: same as for all combined hormal contraceptives
  • Efficacy: perfect use >99%, typical use 91%
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32
Q

For COCP, discuss how it should be taken

A

Standard regime

  • Take pill each day (21 days)
  • When finish pack have 7 day pill free break

Other regimes exist such as everyday pills (28 pills in a pack, last 7 are inactive pills. Take packs back to back/pill every day. Still get bleed when take inactive pills); tailored regimes (e.g. don’t have a pill free break, only break for 4 days etc…)

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33
Q

For COCP, discuss when in the menstrual cycle it should be started

A
  • Take on day 1-5 of menstrual cycle and you won’t require any additional precautions
  • If start pill after day 5 of menstrual cycle need extra precautions for 7 days
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34
Q

Discuss advantages & disadvantages of COCP

A

Advantages

  • it does not interrupt sex
  • it usually makes your bleeds regular, lighter and less painful
  • it reduces your risk of cancer of the ovaries, womb and colon
  • it can reduce symptoms of PMS
  • it can sometimes reduce acne
  • it may protect against pelvic inflammatory disease
  • it may reduce the risk of fibroids, ovarian cysts and non-cancerous breast disease

Disadvantages

  • it can cause temporary side effects at first, such as headaches, nausea, breast tenderness and mood swings
  • it can increase your blood pressure
  • it does not protect you against STIs
  • breakthrough bleeding and spotting is common in the first few months of using the pill
  • it has been linked to an increased risk of some serious health conditions, such as blood clots and breast cancer
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35
Q

For COCP, discuss the missed pill rules (2 circumstances)

A
  • If 2–7 pills have been missed (72 hours or more since the last pill in the current pack was taken) in week 1 after HFI advise the woman to:
    • Take extra precautions for 7 days
    • Consider emergency contraception is UPSI occured in HFI or week 1
    • Take most recent missed pill asap
    • Continue taking remaining pills at same time
  • If it has been 9 completed days or more since the last active pill was taken when restarting the pill after the hormone-free interval (HFI). Advise woman same as above.

NOTE: if there were 2 or more missed pills in the week leading up to HFI omit the HFI

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36
Q

Dicuss what a woman should do if they have had vomiting or diarrhoea when taking COCP

A

Vomitting

  • If you vomit within 3 hours of taking pill, take another pill and then take next pill at usual time
  • If you continue to vomit, follow missed pill rules (counting each day of vomitting as a missed pill)

Diarrhoea

  • If severe diarrhoea, 6-8 watery poos per day, may not absorb pill; keep taking your pill as normal, but use additional contraception, such as condoms, while you have diarrhoea and for 2 days after recovering.
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37
Q

State some examples of COCPs

A
  • Microgynon 30
  • Levest
  • Millinette

(LOTS OF THEM)

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38
Q

For the proesterone only pill (POP), discuss:

  • Mechanism of action
  • Indications
  • Contraindications
  • Important ADRs
  • Efficacy
A
  • Releases low dose progesterone; low dose of progesterone not enough to inhibit ovulation hence main principle of action is to thicken cervical mucus & prevent entry of sperm. Also thin endometrial lining to reduce chance of implantation & reduce cilia function in fallopian tubes. *** NOTE: The desogestrel progestogen-only pill can also stop ovulation​ (97%); get varying degrees of supression of ovulation in other pills
  • Indications:
    • Not suitable for COCP (e.g. you can take POP if >35yrs and you smoke)
    • Don’t want implant/device/injection
    • Regular sex
    • Don’t need STI protection
  • Contraindications:
    • are pregnant
    • have breast cancer (ONLY UKMEC4)
    • have severe liver cirrhosis
    • have liver tumours
  • ADRs:
    • Menstrual irregularities.
    • Breast tenderness
    • Headaches
    • Acne
    • Ovarian cysts.
    • A possible increased risk of breast cancer
  • Efficacy: perfect use >99%, typical use 91%
39
Q

State 3 types of progesterone only pill licensed for use in UK

A
  • Levonorgestrel
  • Norethisterone
  • Desogestrel
40
Q

Describe how POP should be taken

A

Progestogen-only pills should be taken daily at the same time each day for 28 days, with no pill-free interval.

Two types of POP:

  • 3-hour progestogen-only pill (traditional progestogen-only pill) – must be taken within 3 hours of the same time each day
  • 12-hour progestogen-only pill (desogestrel progestogen-only pill) – must be taken within 12 hours of the same time each day
41
Q

Discuss advantages & disadvantages of POP

A

Advantages

  • it does not interrupt sex
  • you can use it when breastfeeding
  • it’s useful if you cannot take the hormone oestrogen
  • you can use it at any age

Disadvantages

  • you may not have regular periods while taking it – your periods may be lighter, more frequent, or may stop altogether, and you may get spotting between periods
  • it does not protect you against STIs
  • you need to remember to take it at or around the same time every day
  • some medicines, including some (uncommon) antibiotics, can make it less effective
42
Q

Discuss the missed pill rules for POP

A

Firslty must clarify which POP she is taking (3 or 12hr):

  • For desogestrel pill, a missed pill is a pill that is >12 hours late
  • For all other POPs, a missed pill is a pill that is >2 hours late

If woman has a missed a pill she should:

  • Take a pill asap
  • Take next pill at normal time
  • Use barrier contraception for next 48hr (unless she is <6 months post partum and exclusively breastfeeding and ammenorrhoeic)
43
Q

Discuss when in the menstrual cycle you should start POP

A
  • Start day 1-5 of menstrual cycle
  • If start after day 5, use other precautions for 48hr
44
Q

Discuss what a woman should do if she experiences vomitting and/or diarrhoea whilst taking POP

A

Vomitting

If vomit within 2 hours of taking pill, take another one asap then continue taking other pills as usual

If vomitting persists then count each day as missed pill and follow missed pill rules

Diarrhoea

  • Use extra precuations during and for 48hrs after illness
45
Q

State some examples of progesterone only pills, include an example of traditional and example of desogestrel only pill

A
  • Traditional progestogen-only pill (e.g. Norgeston or Noriday)
  • Desogestrel-only pill (e.g. Cerazette)
46
Q

For the contraceptive implant, discuss:

  • Mechanism of action
  • Indications
  • Contraindications
  • Important ADRs
  • Efficacy
A
  • Releases high dose progesterone which inhibits ovulation (main), thickens cervical mucus & thins endometrium, decrease cilia function in fallopian tubes. Inhibits ovulation by inhibitin positive feedback of oestrogen and therefore inhibiting LH surge.
  • Indications:
    • Doesn’t need STI protection
    • Wants long term (3yrs) contraception
    • Oestrogen contraindicated
  • Contraindications:
    • Pregnant
    • Breast cancer (ONLY UKMEC 4)
    • Liver cirrhosis
    • Liver tumours
    • Certain medications
    • Unexplained vaginal bleeding
    • Stroke or coronary artery disease
  • ADRs:
    • Menstrual irregularities.
    • Breast tenderness.
    • Ovarian cysts.
    • Headaches
    • Acne
    • A possible increased risk of breast cancer
  • Efficacy: >99%
47
Q

Discuss where the contraceptive implant should be inserted

A
48
Q

Describe the procedure for implanting contraceptive implant

How long can it be in for?

A
  • Insert on day 1-5 of menstrual cycle and don’t need to use extra precautions (if insert after day 5 need to use extra precautions for 7 days)
  • Local anaesthetic e.g. Lidocaine is used
  • Insert 1/3 way up medial side of upper arm, beneath skin and above subcutaneous fat
  • Should be able to press one end down and other end pop up against skin
  • Must be changed after 3yrs

Specific qualifications are also required to remove the implant. Lidocaine is used as a local anaesthetic. The device is located, and a small incision is made in the skin at one end. The device is removed using pressure on the other end or forceps. Require contraception immediately after.

49
Q

How quickly does fertility return following use of contraceptive implant

A

Normal fertility should return as soon as implant removed

50
Q

Discuss advantages & disadvantages of contraceptive implant

A

Advantages

  • Effective and reliable contraception
  • It can improve dysmenorrhoea It can make periods lighter or stop all together
  • No need to remember to take pills
  • It does not cause weight gain (unlike the depo injection)
  • No effect on bone mineral density (unlike the depo injection)
  • No increase in thrombosis risk (unlike the COCP)
  • No restrictions for use in obese patients (unlike the COCP)

Disadvantages

  • It requires a minor operation with a local anaesthetic to insert and remove the device
  • It can lead to worsening of acne
  • There is no protection against sexually transmitted infections
  • It can cause problematic bleeding
  • Implants can be bent or fractured
  • Implants can become impalpable or deeply implanted, leading to investigations and additional management
51
Q

What implant is used in UK and what progesterone does it release?

A
  • Nexplanon
  • 68mg of etonogestrel
  • Licensed for ages 19-40yrs
52
Q

Rarely, the contraceptive implant can become impalpable or deeply implanted; what should you advise women in regards to this?

What investigations would be done?

A
  • Advise women to regularly check implant- should be able to push one end down and other end press up against skin
  • If can’t do this:
    • Contact GP/nurse
    • Use extra conctraception
    • Consider pregnancy test

Investigations may need to done and removal may be required at specialist centre. Investigations include:

  • Ultrasound
  • X-ray (manufacturers add barium sulphate to make radio-opaque)
  • CXR (if suspect had migrated)
53
Q
A
54
Q

For the progesteron injection (DEPO injection/DMPA), discuss:

  • Mechanism of action
  • Indications
  • Contraindications
  • Important ADRs
  • Efficacy
A
  • Injection of high dose progesterone; inihibits negative feedback of oestrogen to inhibit FSH & LH surge and therefore inhibit ovulation. Also thickens cervical mucus, thins endometrium and decreses cilia function in fallopian tubes.
  • Indications:
    • Don’t need STI protection
    • Don’t want to get pregnant in near futur
    • Can’t have oestrogen
  • Contraindications:
    • Active breast cancer (UKMEC 4)
    • Ischaemic heart disease & stroke (UKMEC 3)
    • Unexplained vaginal bleeding (UKMEC 3)
    • Severe liver cirrhosis (UKMEC 3)
    • Liver cancer (UKMEC 3)
    • >45yrs (UKMEC 2)
  • Important ADRs:
    • Weight gain
    • Acne
    • Reduced libido
    • Mood changes
    • Headaches
    • Flushes
    • Hair loss (alopecia)
    • Skin reactions at injection sites
    • Irregular bleeding (usually resolve after 1yr and have amorrhoea)
    • Small increased risk breast & cervical cancer
    • Osteoporosis risk
  • Efficacy: 94%
55
Q

Explain why there is an increased risk of osteoporosis with progesterone injection

A
  • High dose of progesterone
  • Inhibit positive feedback oestrogen
  • Inhibit FSH & LH
  • FSH stimulates follicles, follicles produce oestrogen
  • Decreased oestrogen production
  • Oestrogen inhibits osteoclasts
56
Q

There are two versions of the depot medroxyprogesterone acetate (DMPA); describe each of these and how they are administered

A

There are two versions commonly used in the UK, all containing medroxyprogesterone acetate. Inject at 12-13 week intervals:

  • Depo-Provera: given by intramuscular injection
  • Sayana Press: a subcutaneous injection device that can be self-injected by the patient
57
Q

Alongside the two versions of depot medroxyprogesterone acetate (DMPA) there is another contraceptive injection; state the name of this and when it is used

A

Noristerat is an alternative to the DMPA that contains norethisterone and works for eight weeks. This is usually used as a short term interim contraception (e.g. after the partner has a vasectomy) rather than a long term solution.

58
Q

Discuss when in the menstrual cycle you should start the progesterone injection

A
  • Start day 1-5 no extra precautions are required
  • Start after day 5 extra precautions are required for 7 days
59
Q

Discuss advantages & disadvantages of progesterone injection

A

Advantages

  • each injection lasts for either 8 or 13 weeks
  • it does not interrupt sex
  • you do not have to remember to take a pill every day
  • it’s safe to use while you’re breastfeeding
  • it’s not affected by other medicines
  • it may reduce heavy, painful periods and help with premenstrual symptoms for some women
  • reduce severity of sickle celll crisis is sickle cell anaemia

Disadvantages

  • your periods may change and become irregular, heavier, shorter, lighter or stop altogether – this can carry on for some months after you stop the injections
  • it does not protect you against STIs
  • there can be a delay of up to 1 year before your periods return to normal and you can become pregnant
  • some people may put on weight
  • you may experience side effects like headaches, acne, hair loss, decreased sex drive and mood swings
  • any side effects can continue for as long as the injection lasts (8 or 13 weeks) and for some time after
60
Q

Discuss how much earlier than planned the progesterone injection can be given

Discuss how much later than planned the progesterone injection can be given and still provide protection?

A
  • Can be given as early as 10 weeks
  • Can be given as late as 14 weeks and still provide protection

*DELAYING AFTER 13 WEEKS INCREASES CHANCE OF PREGNANCY

61
Q

Discuss what a woman should do if she is late receiving her injection

A
  • Up to 14 weeks (1 week late): no contraception needed
  • >14 weeks: other precuations needed for 7 days, consider emergency contraception
62
Q

State the two types of intrauterine device and describe their mechanism of action

A
  • IUD (intrauterine device): contains copper which induces an inflammatory reaction in endometrium/creates hostile environment preventing implanatation. Copper is also toxic to sperm & ova
  • IUS (intrauterine system): contains progestogen that is slowly released into the uterus (locally). Works by providing physical barrier to implantation and thinning the endometrium to prevent implantation. Also thickens cervical mucus.
63
Q

For the intrauterine device (IUD and IUS) discuss:

  • Indications
  • Contraindications
  • Important ADRs/risks
A
  • Indications:
    • Long term contraception
    • Don’t need protection against STIs
    • Can’t have oestrogen
  • Contraindications:
    • Pelvic inflammatory disease or infection
    • Immunosuppression
    • Pregnancy
    • Unexplained bleeding
    • Pelvic cancer
    • Uterine cavity distortion (e.g. by fibroids)
  • Important ADRs:
    • Pelvic pain
    • Uterine perforation
    • Increased risk of infection following insertion of IUD
    • Abnormal uterine bleeding (usually stop after 6 months)
64
Q

Describe how the intrauterine devices are inserted

A
  • Screen for chlamydia & gonorrhoea in those who are at increased risk (e.g. <25yrs)
  • Bimanual pelvic examination to check position & size of uterus
  • Speculum is inserted and specialised equipment is used to insert device
  • BP & HR are measured before & after insertion
  • Advise to take NSAIDs (or paracetamol if can’t take NSAIDs) for crampy pain following insertion
  • Follow up in 3-6 weeks after insertion to check the threads
  • Women should be taught to feel the strings to ensure the coil is in place
65
Q

If coil threads cannot be seen or palpated, what 3 things must be excluded?

What investigations should be performed?

A

Must exclude:

  • Expulsion
  • Pregnancy
  • Perforation

Extra precautions are required until device is located.

Investigations:

  • First line= ultrasound
  • Second line= abdo & pelvic x-ray
  • Third line= hysteroscopy or laparoscopic surgery
66
Q

How long can each of the following be used for:

  • IUD
  • IUS
A
  • IUD= 5-10yrs
  • IUS= 3-5yrs
67
Q

Which of the intrauterine devices can be used as emergency contraception?

A

IUD can be used as emergency contraception if they present:

  • Up to 120hrs after first episode of UPSI
  • In a cycle up to 5 days after earliest expected date of ovulation
68
Q

What disease is IUD contraindicated in?

A

Wilson’s disease

69
Q

State some advantages & disadvantages of IUD

A

Advantages

  • Reliable contraception
  • It can be inserted at any time in the menstrual cycle and is effective immediately
  • It contains no hormones, so it is safe for women at risk of VTE or with a history of hormone-related cancers
  • It may reduce the risk of endometrial and cervical cancer

Disadvantages

  • A procedure is required to insert and remove the coil, with associated risks
  • It can cause heavy or intermenstrual bleeding (this often settles)
  • Some women experience pelvic pain
  • It does not protect against sexually transmitted infections
  • Increased risk of ectopic pregnancies
  • Intrauterine devices can occasionally fall out (around 5%)
70
Q

State some advantages & disadvantages of IUS

A

Advantages

  • It can make periods lighter or stop altogether
  • It may improve dysmenorrhoea or pelvic pain related to endometriosis
  • No effect on bone mineral density (unlike the depo injection)
  • No increase in thrombosis risk (unlike the COCP)
  • No restrictions for use in obese patients (unlike the COCP)
  • The Mirena has additional uses (i.e. HRT and menorrhagia)

Disadvantages

  • A procedure is required to insert and remove the coil, with associated risks
  • It can cause spotting or irregular bleeding
  • Some women experience pelvic pain
  • It does not protect against sexually transmitted infections
  • Increased risk of ectopic pregnancies
  • Increased incidence of ovarian cysts
  • There can be systemic absorption causing side effects of acne, headaches, or breast tenderness
  • Intrauterine devices can occasionally fall out (around 5%)
71
Q

Irregular/problematic bleeding can occur in the first 6 months of of IUS insertion; what do FSRH reccomend for this?

A

Taking COCP in combination with IUS for 3 months to help settle bleeding

72
Q

What organisms are often discovered incidentally when doing smear tests in women with intrauterine devices?

Does this require treatment?

A
  • Actinomyces-like organisms
  • Doesn’t require treatment unless symptomatic
73
Q

State the 4 types of IUS

A

There are four types of IUS you may come across, all containing levonorgestrel:

  • Mirena: effective for 5 years for contraception, and also licensed for menorrhagia and HRT
  • Levosert: effective for 5 years, and also licensed for menorrhagia
  • Kyleena: effective for 5 years
  • Jaydess: effective for 3 years

TOM TIP: The IUS to remember is the Mirena coil. It is commonly used for contraception, menorrhagia and endometrial protection for women on HRT. It is licensed for 5 years for contraception, but only 4 years for HRT.

74
Q

What is the efficacy of intrauterine devices?

A

99%

75
Q

For sterilisation in females, discuss:

  • What is done
  • How it works
  • Failure rates
  • Advice on contraception following procedure
A
  • Most common method of sterilisation is tubal occlusion: typically performed by laparoscopy under general anaesthesia, with occlusion of the tubes using “Filshie clips”. Alternatively, the fallopian types can be tied and cut, or removed altogether. This can be done as an elective procedure, or during a caesarean section.
  • Prevents ovum travelling from the ovary to the uterus along the fallopian tube
  • Failure rate 1 in 200
  • Alternative contraception required until next menstrual cycle (in case ovum has already reached uterus)
76
Q

For sterilisation of males, discuss:

  • What is done
  • How it works
  • Failure rate
  • Advice following procedure
A
  • Cut vas deferens (vasectomy). Done under local anaesthetic. Takes 15-20 mins, less invasive then female sterilisation therefore reccommended for couples who don’t want children.
  • Prevents sperm from being released into vagina
  • Failure rate: 1 in 2000
  • Use alternative contraception for few months after procedure until semen testing can be done, about 12 weeks after procedure, to ensure it has worked. have to wait 12 weeks before test as it takes time for sperm in still in tubes to be cleared.
77
Q

What 3 post-coital contraception options does a woman have?

A
  • Levonorgestreal (Levonelle)
  • Ulipristal acetate (ellaONE)
  • IUD
78
Q

For the post-coital contraceptive Levonelle (levonorgestrel), discuss:

  • Mode of action
  • Indications
  • Contraindications
  • Correct use
  • What to do if vomitting occurs
  • Important ADRs
  • Efficacy
A
  • Inhhibit ovulation for 5-7 days.
  • Indications:
    • Present within 72hrs of unprotected sex or contraceptive failure
  • Contraindications:
    • _​_Use with caution in current active breast cancer
  • Take 1.5mg single dose within 72hrs. Continue use of normal contraception. *NOTE: can double dose if on liver enzyme inducing drugs or if BMI >26kg/m2 or >70kg
  • If vomits within 3hrs, must take another pill. Clinicians should consider antiemetic drug also.
  • Important ADRs:
    • Nausea & vomitting
    • Menstrual irregularlities
    • Dizziness
    • Diarrhoea
    • Breast tenderness
  • Efficacy: 0.6-3.1% become pregnant *NOTE: decreased efficacy in pts with high BMI
79
Q

For the post-coital contraceptive ulipristal acetate (EllaONE), discuss:

  • Mode of action
  • Indications
  • Contraindications
  • Correct use
  • What to do if vomitting occurs
  • Important ADRs
  • Efficacy
A
  • Progesterone receptor modulator that can inhibit or delay ovulation
  • Indications: must present within 5 days (120hrs) of UPSI/contraceptive failure
  • Contraindications: cannot take twice in one cycle (e.g. if have UPSI twice in one cycle- different if vomitted)
  • Take orally as single 30mg tablet
  • If vomit within 3 hrs, another dose is required
  • Important ADRs:
    • ​GI upset
    • Menstrual irregularities
    • Headaches
    • Breast tenderness
    • Nausea & vomitting
    • Dizziness
  • Efficacy: 0.9-2.1% become pregnant
80
Q

For the post-coital contraceptive IUD, discuss:

  • Mode of action
  • Indications
  • Contraindications
  • Important ADRs
  • Advice following insertion
  • Efficacy
A
  • Copper is toxic to the ovum and sperm, so the Cu-IUD is effective immediately after insertion and works primarily by inhibiting fertilization. If fertilization has already occurred, the Cu-IUD has an anti-implantation effect.
  • Indications: present within 5 days of UPSI/contraceptive failure
  • Contraindications: usual for IUD (STIs, PID, uterine abnormalities)
  • Important ADRs:
    • Pelvic infections
    • Uterine perforations
    • Pelvic pain
    • Bleeding
    • Expulsion of IUD
  • Advice following insertion: check up in 3-6 weeks to check it is in place. If she wishes to have it removed after it has been used as emergency contraception she should attend in first few days of onset of menstruation or avoid sexual intercourse for 7 days prior to removal
  • Efficacy: <0.1% get pregnant
81
Q

State some advantages & disadvantages of Levonelle (levonorgestrel) post-coital contraception

A

Advantages

  • Can be used more than once in one cycle
  • Readily available
  • No insertion of a device/procedure

Disadvantages

  • Less suitable for women on liver enzyme inducing drugs
  • Can cause nausea & vomitting; may need to tkae second tablet if this occurs
  • Only suitable up to 72hrs after UPSI/contraceptive failure
82
Q

State some advantages & disadvantages of EllaONE (ulipristal acetate)

A

Advantages

  • Readily available
  • No device insertion/procedure

Disadvantages

  • Can only be taken once in one cycle
  • May cause vomitting in which case need to take second tablet
  • Not suitable for those taking liver enzyme inducing drugs
  • If woman is breastfeeding, she must avoid breastfeeding for 1 week
83
Q

State some advantages & disadvantages of the IUD as an emergency contraceptive

A

Advantages

  • Most effective
  • Can be left in place as long term contraception
  • Fertility returns as soon as its removed

Disadvantages

  • Less readily available
  • Procedure to insert
  • May experience pelvic pain after insertion
  • Potential complications
84
Q

Put the following post-coital contraceptives in order of efficacy (start with highest efficacy)

A
  • IUD
  • Ulipristal acetate (EllaONE)
  • Levonorgestrel (Levonelle)
85
Q

What contraceptives might you offer a women who has heavy/painful periods?

A

Offer contraception with progesterone in it as this thins the endometrial lining to make periods lighter.

86
Q

State some forms of contraceptino that would be suitable for someone who is wanting to start a family soon

A
  • Progesterone implant
  • IUD
  • IUS
  • Diaphragm or cap
  • Progesterone only pill
  • Male or female condoms
87
Q

What are the UKMEC criteria (for contraceptive use)?

A
  • UK Medical Eligibility Criteria
  • Offers guidance to providers of contraception regarding who can use which contraceptive methods safely
  • Evidence based reccommendations do not indicate a best method for a woman nor do they take into account efficacy
  • They are there to faciliate discussion with patients and help clinicians narrow down safe options for patients
88
Q

There are 4 UKMEC categories; define each category

A
89
Q

What are the main issues about capacity & consent in young people- in relation to sex and contraception?

A
  • Are they old enough to be having sex (>16yrs)?
  • Who are they having sex with? How old are they?
  • Are they mature enough to make those decisions?
  • Are they aware of potential risk & consequences?
  • Is there a safeguarding issue?
  • Are they taking contraception?
  • Are their parents aware? Do they or do they not want their parents to be aware?
90
Q

What is Gillick competency?

A

When practioners are trying to decide whether a child is maturen enough to make decisions about things that affect them they often talk about whether the child is ‘Gillick competent’ or whether they meet the Fraser guidelines. There is no set of defined questions to assess Gillick competency; professionals need to consider several things when assessing a child’s capacity to consent- including:

  • Age, maturity & mental capacity
  • Understanding of the issue & what it involves
  • Understand of risks and consequences
  • How well they understand advice been given
  • Understanding of alternative options
  • Their ability to explain rationale around their reasoning & decision making
91
Q

What are the Fraser guidelines?

A

Fraser guideliens apply specifically to advice & treatment about contraception & sexual health. They may be used by a range of healthcare professionals working with under 16yr olds.

Pracitioners should be satisfied of the following:

  • Young person cannot be persuaded to inform their parents or carers that they are seeking advice for treatment
  • Young person understands advice being given
  • Young person’s physical or mental health or both are likely to suffer unless they receive advice or treatment
  • It is in young persons best interest to receive advice, treatment or both wihtout the parents/carers consent
  • Young person is very likely to continue having sex with or without contraception
92
Q

What are the main issues around capacity & consent (both around contraception & sexual consent) amongst patients with learning disability?

A
  • Do they understand what they are consenting to? (Benefits, risks, potential consequences)
  • Do they understand safe sex?
  • Safe guarding issue?
  • If they became pregnant, do they have capacity/strength to deal with that?
  • They are human; want to enjoy same things as everyone else.
93
Q

State some drugs that are known to interact with combined oral contraceptives, progestogen-only oral contraceptives, contraceptive patches , vaginal rings, and emergency hormonal contraception

A

Drugs that induce hepatic enzyme activity (e.g. carbamazepine, eslicarbazepine acetate, nevirapine, oxcarbazepine, phenytoin, phenobarbital, primidone, ritonavir, St John’s wort, topiramate and, above all, rifabutin and rifampicin ) and possibly also griseofulvin.