ID- Soft tissue treatments

Question 1

Nonpurulent cellulitis

Answer 1

Empiric treatment for B-hemolytic streptococci and MSSA

• Dicloxacillin, cephalexin, clinda (all oral)
• IV antibiotics for unsuccessful outpatient treatment or patients with signs of toxicity

Question 2

Purulent cellulitis, mild to moderate severity

Answer 2

Empiric treatment of MRSA

- Clinda, bactrim, doxy

Question 3

Purulent cellulitis with extensive disease or signs of systemic toxicity

Answer 3

• Vanc (IV) or linezolid (oral or IV), daptomycin, telavancin, ceftaroline

Question 4

Impetigo

Answer 4

Extensive disease, treat as nonpurulent cellulitis; limited disease, mupirocin (topical) or amox (oral)

Question 5

Folliculitis (staph and pseudomonal)

Answer 5

Spontaneous resolution is typical, Topical mupirocin or clinda lotion can be used

Question 6

Human bites (clenched fist injury)

Answer 6

Ampicillin-sulbactam (IV)

Question 7

Animal bites

Answer 7

Amp-sulbactam (IV) or amox-clav (oral)

Question 8

Neutropenia

Answer 8

Vanc and cefepime

Question 9

Necrotizing fasciitis, compartment syndrome, myonecrosis on imaging, purple bullae or sloughing of skin

Answer 9

Imipenem, clinda, vanc, and prompt debridement

Question 10

Erythrasma

Answer 10

Topical erythromycin, clarithromycin, or clinda