ID - Antimicrobials Flashcards
Penicillins
- Benzylpenicillin (Penicillin G) and related drugs
- Antistaphylococcal penicillins
- Aminopenicillins
- Extended spectrum penicillins (Antipseudomonal penicillins)
Penicillin (PCN) susceptibility
- Streptococci
- Sensitive enterococci
- Listeria
- Syphilis
Semisynthetic penicillins
= penicillinase-resistant penicillins
= lactamase-resistant penicillins
= antistaphylococcal penicillins
- Methicillin
- Oxacillin
- Nafcillin
- Dicloxacillin
- Cloxacillin,
- Flucloxacillin
Aminopenicillins
- Ampicillin (IV)
- Amoxicillin (Oral)
Aminopenicillins (amoxicillin, ampicillin) susceptibility
Penicillin (but not semisynthetic penicillins) susceptible organisms plus:
- H influenzae
- E coli
- Proteus mirabilis
- Salmonella
- Shigella
Anti-pseudomonal penicillins
- Piperacillin
- Ticarcillin
Anti-pseudomonal penicillins susceptibility
Ampicillin susceptible organisms plus
- Pseudomonas
Beta-lactamase inhibitors
- Sulbactam
- Tazobactam
- Avibactam
- Clavulanic acid
Beta-lactam antibiotics
- Penicillin
- Cephalosporins
- Monobactams
- Carbapenem
They share a ß-lactam ring in their molecular structure.
Organisms capable of producing penicillinase
- Staphylococcus aureus,
- Escherichia coli,
- H. influenzae
- Pseudomonas aeruginosa
- Neisseria gonorrhoeae
- Proteus
- Bacteroides species.
Aminoglycosides
Gentamicin
Tobramycin
Amikacin
Neomycin
Streptomycin
Kanamycin
Glycopeptides
Vancomycin
Teicoplanin
Telavancin
Oritavancin
Dalbavancin
