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Pharm > ID > Flashcards

ID Flashcards

1
Q

ketoconazole

A

topical and systemic

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2
Q

clotrimazole/miconazole

A

topical only

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3
Q

ciclopiroxolamine

A

topical only/ interferes with DNA/RNA synthesis

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4
Q

griseofulvin

A

systemic/ inhibits mitosis/ teratogenic, EtOH reaction

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5
Q

terbinafine

A

topical and systemic/ blocks synthesis of ergosterol

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6
Q

systemic azoles

A

inhibit fungal and human CYP450

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7
Q

itraconazole

A

systemic/ active against fluconazole resistant candidas/ variable absorption

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8
Q

voriconazole

A

systemic/ aspergillus/ vision changes

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9
Q

posaconazole

A

systemic/ mucormycosis and zygomycosis/ thrombophlebitis

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10
Q

isavuconazole

A

systemic/ similar to posaconazole/ isavuconazonium prodrug

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11
Q

echinocandins

A

inhibit beta (1,3) synthesis/ yeasts and molds/ fungistatic, fungicidal against candida/ parenteral only

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12
Q

amphotericin B

A

bind to ergosterol/ fungicidal/ yeasts and molds/ parenteral only

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13
Q

fluconazole

A

systemic/ not active against molds

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14
Q

metronidazole/tinidazole

A

symptomatic amebiasis/ alcohol reaction, CNS dysfuntion

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15
Q

paromomycin

A

luminal agent

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16
Q

chloroquine

A

malaria/ vivid dreams, visual changes/ haiti

17
Q

quinine

A

chloroquine resistant malaria/ cinchonism/ G6PD, thrompocytopenia, hemolytic anemia

18
Q

mefloquine

A

malaria prophylaxis/ neuropsychiatric, vivid dreams/ 1x week

19
Q

atovaquone+proguanil

A

malaria prophylaxis/ every day

20
Q

artemether

A

resistant malaria treatment

21
Q

primaquine/tafenoquine

A

liver/tissue malaria/ G6PD

22
Q

albendazole

A

round worms, tapeworms, hookworms/ more absorption with food

23
Q

mebendazole

A

pinworms

24
Q

ivermectin

A

round worms/ paralytic

25
Q

pyrantel pamoate

A

pinworms, hookworms/ paralytic

26
Q

praziquantel

A

tapeworms/ schisto/ plasma membrane-calcium

27
Q

ganciclovir

A

antiherpes/CMV

28
Q

abacavir

A

NRTI/ HIV combination drug

29
Q

emtricitabine

A

NRTI/ first line HIV HBV

30
Q

tenofovir

A

NtRTI/ first line HBV HIV/ decreased bone density, nephrotoxicity

31
Q

efavirenz

A

NNRTI/ HIV treatment/ microcephaly, CNS

32
Q

integrase inhibitors

A

-gravir

33
Q

ritonavir

A

protease inhibitor/ boosts other antivirals

34
Q

darunavir

A

protease inhibitor/ HIV treatment

35
Q

oseltamivir

A

tamiflu

36
Q

nystatin

A

binds ergosterol/ not effective against dermatophytes

37
Q

indinavir

A

protease inhibitor/ crystal induced nephropathy

Pharm (10 decks)

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