ID

Question 1

ketoconazole

Answer 1

topical and systemic

Question 2

clotrimazole/miconazole

Answer 2

topical only

Question 3

ciclopiroxolamine

Answer 3

topical only/ interferes with DNA/RNA synthesis

Question 4

griseofulvin

Answer 4

systemic/ inhibits mitosis/ teratogenic, EtOH reaction

Question 5

terbinafine

Answer 5

topical and systemic/ blocks synthesis of ergosterol

Question 6

systemic azoles

Answer 6

inhibit fungal and human CYP450

Question 7

itraconazole

Answer 7

systemic/ active against fluconazole resistant candidas/ variable absorption

Question 8

voriconazole

Answer 8

systemic/ aspergillus/ vision changes

Question 9

posaconazole

Answer 9

systemic/ mucormycosis and zygomycosis/ thrombophlebitis

Question 10

isavuconazole

Answer 10

systemic/ similar to posaconazole/ isavuconazonium prodrug

Question 11

echinocandins

Answer 11

inhibit beta (1,3) synthesis/ yeasts and molds/ fungistatic, fungicidal against candida/ parenteral only

Question 12

amphotericin B

Answer 12

bind to ergosterol/ fungicidal/ yeasts and molds/ parenteral only

Question 13

fluconazole

Answer 13

systemic/ not active against molds

Question 14

metronidazole/tinidazole

Answer 14

symptomatic amebiasis/ alcohol reaction, CNS dysfuntion

Question 15

paromomycin

Answer 15

luminal agent

Question 16

chloroquine

Answer 16

malaria/ vivid dreams, visual changes/ haiti

Question 17

quinine

Answer 17

chloroquine resistant malaria/ cinchonism/ G6PD, thrompocytopenia, hemolytic anemia

Question 18

mefloquine

Answer 18

malaria prophylaxis/ neuropsychiatric, vivid dreams/ 1x week

Question 19

atovaquone+proguanil

Answer 19

malaria prophylaxis/ every day

Question 20

artemether

Answer 20

resistant malaria treatment

Question 21

primaquine/tafenoquine

Answer 21

liver/tissue malaria/ G6PD

Question 22

albendazole

Answer 22

round worms, tapeworms, hookworms/ more absorption with food

Question 23

mebendazole

Answer 23

pinworms

Question 24

ivermectin

Answer 24

round worms/ paralytic

Question 25

pyrantel pamoate

Answer 25

pinworms, hookworms/ paralytic

Question 26

praziquantel

Answer 26

tapeworms/ schisto/ plasma membrane-calcium

Question 27

ganciclovir

Answer 27

antiherpes/CMV

Question 28

abacavir

Answer 28

NRTI/ HIV combination drug

Question 29

emtricitabine

Answer 29

NRTI/ first line HIV HBV

Question 30

tenofovir

Answer 30

NtRTI/ first line HBV HIV/ decreased bone density, nephrotoxicity

Question 31

efavirenz

Answer 31

NNRTI/ HIV treatment/ microcephaly, CNS

Question 32

integrase inhibitors

Answer 32

-gravir

Question 33

ritonavir

Answer 33

protease inhibitor/ boosts other antivirals

Question 34

darunavir

Answer 34

protease inhibitor/ HIV treatment

Question 35

oseltamivir

Answer 35

tamiflu

Question 36

nystatin

Answer 36

binds ergosterol/ not effective against dermatophytes

Question 37

indinavir

Answer 37

protease inhibitor/ crystal induced nephropathy