ID Flashcards

1
Q

Which enzymes catalyse formation of components of the fungal cell wall?

A

Synthase enzymes

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2
Q

What is the main sterol in fungi?

A

Ergosterol

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3
Q

Which enzyme do allylamines inhibit?

A

Squalene epoxidase

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4
Q

What do azoles inhibit?

A

Cytochrome P450 14-DM

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5
Q

How is AMB (Amphotericin B) infused?

A

IV, every 48-72 hours until total cumulative dosage has been reached

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6
Q

What form the structural basis of a fungal cell wall?

A

Cross-linked glycoprotein, glucan and chitin

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