Ibuprofen

Question 1

Drug code for Ibuprofen?

Answer 1

IBP

Question 2

Presentation of Ibuprofen?

Answer 2

Solution or suspension containing Ibuprofen 100 milligrams in 5ml (Ibuprofen 20mg in 1ml)
Tablet containing 200 milligrams or 400 milligrams Ibuprofen

Question 3

Indications for use of Ibuprofen?

Answer 3

Relief of mild or moderate pain
Pyrexia with discomfort (may help to relieve misery and often unpleasant symptoms that often accompany febrile illness e.g. aches and pains)
Soft tissue injuries
Best when used as a part of a balanced analgesic regimen

Question 4

What is pyrexia?

Answer 4

abnormal elevation of body temperature : fever

Question 5

Actions of Ibuprofen?

Answer 5

Analgesic (relieves pain)
Antipyretic (reduces temperature)
Anti-inflammatory (reduces inflammation)

Question 6

Contra-indications of Ibuprofen?

Answer 6

DO NOT administer if the patient is:

• Dehydrated
• Hypovolaemic
• known to have renal insufficiency
• Patients with active upper gastrointestinal disturbance
• A woman in the last trimester of pregnancy
• A child with chickenpox
• A patient who has previously shown hypersensitivity reactions, in response to ibuprofen, aspirin or other non-steroidal anti-inflammatory drugs
• A patient with active peptic ulcer/haemorrhage
• Patient with severe heart failure (NYHA class IV), renal failure or hepatic failure

Question 7

What does It mean If someone is considered hypovolaemic?

Answer 7

Also known as volume depletion or volume contraction, is a state of abnormally low extracellular fluid in the body.
This may be due to either a loss of both salt and water or a decrease in blood volume.
Hypovolemia refers to the loss of extracellular fluid and should not be confused with dehydration.

Question 8

Common examples of hypersensitivity reactions to ibuprofen?

Answer 8

asthma
rhinitis
angioedema
urticaria

Question 9

Common examples of upper gastrointestinal disturbance in patients where ibuprofen should not be given?

Answer 9

oesophagitis
peptic ulcer
dyspepsia

Question 10

When should further non-steroidal anti-inflammatory drugs (NSAIDs), i.e. Ibuprofen not be given?

Answer 10

If an NSAID containing product has been administered within the last 4 hours or if the maximum cumulative daily dose has already been given

Question 11

Cautions of Ibuprofen use in patients with asthma?

Answer 11

Use cautiously in asthmatic patients due to the possible risk of hypersensitivity and bronchoconstriction
If an asthmatic has not use NSAIDs previously, do not use acutely in the pre-hospital setting

Question 12

Cautions of ibuprofen use in older patients?

Answer 12

Exercise caution in older patients ( >65 years old ) that have not used tolerated NSAIDs recently

Question 13

Cautions of ibuprofen use?

Answer 13

Asthma
Older people
Patients with coagulation defects
Crohn’s disease and ulcerative colitis as a condition may be exacerbated
Avoid in patients with established ischaemic heart disease, peripheral arterial disease, cerebrovascular disease, congestive heart failure
Hypertension

Question 14

Side effects of Ibuprofen?

Answer 14

May cause nausea, vomiting and tinnitus

Question 15

Route of administration for ibuprofen?

Answer 15

Oral

Solution or tablet

Question 16

Initial dose of ibuprofen given?

Answer 16

400 milligrams

Question 17

Can a repeat dose of ibuprofen be given?

Answer 17

Yes

400 milligrams

Question 18

Dose interval for ibuprofen?

Answer 18

8 hours

Question 19

Volume of ibuprofen given?

Answer 19

Varies depending on type of oral administration used

Question 20

Maximum dose of ibuprofen that can be given?

Answer 20

1.2 grams per 24 hours

Question 21

At what age can a standard dose of ibuprofen be given?

Answer 21

12 years

Question 22

What should ibuprofen preferably be administered with?

Answer 22

Food