IBD Tx

Question 1

Which drug families are utilized for UC?

Answer 1

5-ASA, TNF-a inhibitor, a-4 Integrin inhibitor

Question 2

When would you use Olsalazine?

Answer 2

UC maintenance

Question 3

When would you use Balsalazide?

Answer 3

Active UC

Question 4

At what severity would you use a 5-ASA drug?

Answer 4

Mild/moderate UC

Question 5

What are the SE to be worried about with TNF-a inhibitors?

Answer 5

TB infection, liver toxicity

Question 6

Which TNF-a inhibitor is used for UC only?

Answer 6

Golimumab

Question 7

Which TNF-a inhibitor is used for CD only?

Answer 7

Certolizumab

Question 8

What SE should you be worried about with a-4 integrin drugs?

Answer 8

PML

Question 9

What other drugs should you not take when on an a-4 integrin?

Answer 9

TNF-a inhibitor

Question 10

When would you use an a-4 integrin drug?

Answer 10

For Tx-resistant IBD

Question 11

Which a-4 integrin can be used in UC and CD?

Answer 11

Vedolizumab

Question 12

Which a-4 integrin is only used in CD?

Answer 12

Natalizumab

Question 13

Which drug families are utilized for CD?

Answer 13

IL-12/23 inhibitors, TNF-a inhibitors, a-4 integrin inhbitors

Question 14

What SE should you be worried about with IL-12/23 inhibitors?

Answer 14

TB infection

Question 15

When are IL-12/23 inhibitors used?

Answer 15

Tx-resistant CD