Ch. 17 Flashcards
Semi-circumferential webs, Paterson-Brown-Kelly or Plummer-Vinson syndromes
Esophageal mucosal webs
Circumferential webs
Schatzki rings
Mallory-Weiss tears
Lacerations
Full thickness esophageal tear
Boerhaave syndrome
Dysphagia with intraepithelial eosinophils
Eosinophilic esophagitis
Mucin producing tumor in distal 1/3 of esophagus causying hematemesis and odynophagia
Adenocarcinoma of esophagus
Dysplastic squamous tumor in middle 1/3 of esophagus causing odynophagia and dysphagia
Squamous cell carcinoma of esophagus
Atrophic gastric body, hyperplastic antrum, beefy red tongue (atrophic glossitis)
Autoimmune gastritis
Dense eosinophilic infiltrates in antrum/pylorus with elevated serum IgE
Eosinophilic gastritis
Increased intraepithelial T cells affecting the entire stomach
Lymphocytic/Varioliform gastritis
Hyperplastic body/fundus causing enlarged rugae, corkscrew glands, hypoplastic chief/parietal cells with chronic ulceration of duodenum/stomach
Menetrier disease
Doubling of oxyntic mucosal thickness from gastrin-secreting tumor
ZE Syndrome
Sharply demarcated ulcers in the stomach with normal adjacent mucosa
Stress ulcer
Ulcers in duodenum associated with severe burns/trauma
Curling ulcer
Ulcers in pts with intracranial disease
Cushing ulcer
Improper branching of artery along lesser curvature of stomach near GE junction
Dieulafoy lesion
Alternating edematous/erythematous mucosa with normal mucosa
Gastric Antral Vascular Ectasia (GAVE)
Lesions in antrum composed of dysplastic epithelium
Gastric adenoma
Well-circumscribed lesions lined by flattened parietal/chief cells
Fundic gland polyps
Signet ring growth with diffuse rugal flattening and “Leather Bottle” appearance
Diffuse gastric adenocarcinoma
Lymphoepithelial lesions expressing CD43 and t(11;18) translocation
MALToma (Lymphoma)
Firm, yellowish mass with intense desmoplasia
Carcinoid tumor
Solitary, well-circumscribed mass with whorled appearance when cut, KIT is diagnostic marker
GI stromal tumor
Broad-based ulcerations causing mucoid dysentery and polyarthritis with ECM1 mutation
Ulcerative colitis
Skip lesions, deep ulcers, cobblestone appearance, non-caseating granulomas with relapsing dysentery, fistulae, and rectal abscesses and NOD2 mutation
Crohn disease
Out-pouching along the taenia coli
Sigmoid diverticulum
Benign, smooth nodular protrusion from colon
Hyperplastic polyp
Pedunculated, reddish lesion in child with rectal bleeding, intussusception, and obstruction and SMAD4 mutation
Juvenile Polyp
Large pedunculated polyp, mucocutaneous hyperpigmentation, and STK11 mutation
Peutz-Jeghers syndrome
Sessile, serrated adenomas with MSH2/MLH1 mutations
Hereditary non-polyposis colorectal cancer
Napkin-ring constrictions in distal colon with APC and SMAD2/4 mutations
Adenocarcinoma
Peritoneal tumor with t(11;22)
Mesothelioma
Chronic diarrhea, bloating, fatigue, dermatitis herpetiformis with HLA-DQ2/8
Celiac disease
Failure to thrive, diarrhea, steatorrhea, presence of “burr” cells on Oil Red-O stain with MTP mutation
Abetalipoproteinemia
Malformed blood vessels occurring in cecum or right colon
Angiodysplasia