GI Bug Tx Flashcards
What drug is first line for CDI Tx?
Vancomycin
What drug is used for recurrent CDI?
Fidaxomicin
Which drugs do you give for E. Histolytica to Tx the invading microbes?
Metronidazole, Tinidazole
Which drugs do you give for E. Histolytica to Tx the intraluminal microbes?
Paromomycin, Lodoquinol
Which drug do you give for Giardia Tx?
Nitazoxanide
What are the SE of Nitazoxanide?
Yellow eyes, bright yellow urine
When would you give a drug for Crypto Parvum Tx?
In immunosuppressed pts
What drug do you give for Crypto Parvum Tx?
Nitazoxanide
Do you continue or discontinue the immunosuppressive drug when treating for Crypto Parvum?
Continue if HIV, discontinue if anything else
How is Necator Americanus/Ancylostoma Duodenale excreted?
Eggs
How is Ascaris Lumbricoides excreted?
Eggs
How is Strongyloides Stercoralis excreted?
Larvae
How is Trichuris Trichiura excreted?
Eggs
How is Enterobius Vermicularis excreted?
Eggs deposited in perianal region
What is the primary drug for Necator Americanus and Ancyclostoma Duodenal Tx?
Albendazole
What are the primary drugs for Ascaris Lumbricoides Tx?
Albendazole, Mebendazole
What is the primary drug for Stronguyloides Stercoralis Tx?
Ivermectin
What is the primary drug for Trichuris Trichiura Tx?
Mebendazole
What are the primary drugs for Enterobius Vermicularis Tx?
Albendazole, Mebendazole, Pyrantel Pamoate
What is the MOA of Albendazole, Mebendazole, and Thiabendazole?
Inhibit microtubule synthesis
What is the MOA of Ivermectin?
Stimulates GABA in peripheral neurons
What is the MOA of Pyrantel Pamoate?
Stimulates Ach and inhibits AchE at NMJ
What is excreted in the feces from Schistosomas?
Eggs
What is excreted in the feces from Taenia Solium/Saginata?
Proglottids
What is excreted in the feces from Diphyllobothrium Latum?
Proglottids
What drug is used to Tx Schistosomas?
Praziquantel
What drug is used to Tx Taenia Solium/Saginata?
Praziquantel
What drug is used to Tx Diphyllobothrium Latum?
Niclosamide
What drug is used to Tx Echinococcus Granulosus?
Praziquantel
What is the MOA of Praziquantel?
Increase Ca permeability of cell membranes causing paraylsis