GI Bug Tx Flashcards

1
Q

What drug is first line for CDI Tx?

A

Vancomycin

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2
Q

What drug is used for recurrent CDI?

A

Fidaxomicin

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3
Q

Which drugs do you give for E. Histolytica to Tx the invading microbes?

A

Metronidazole, Tinidazole

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4
Q

Which drugs do you give for E. Histolytica to Tx the intraluminal microbes?

A

Paromomycin, Lodoquinol

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5
Q

Which drug do you give for Giardia Tx?

A

Nitazoxanide

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6
Q

What are the SE of Nitazoxanide?

A

Yellow eyes, bright yellow urine

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7
Q

When would you give a drug for Crypto Parvum Tx?

A

In immunosuppressed pts

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8
Q

What drug do you give for Crypto Parvum Tx?

A

Nitazoxanide

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9
Q

Do you continue or discontinue the immunosuppressive drug when treating for Crypto Parvum?

A

Continue if HIV, discontinue if anything else

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10
Q

How is Necator Americanus/Ancylostoma Duodenale excreted?

A

Eggs

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11
Q

How is Ascaris Lumbricoides excreted?

A

Eggs

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12
Q

How is Strongyloides Stercoralis excreted?

A

Larvae

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13
Q

How is Trichuris Trichiura excreted?

A

Eggs

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14
Q

How is Enterobius Vermicularis excreted?

A

Eggs deposited in perianal region

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15
Q

What is the primary drug for Necator Americanus and Ancyclostoma Duodenal Tx?

A

Albendazole

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16
Q

What are the primary drugs for Ascaris Lumbricoides Tx?

A

Albendazole, Mebendazole

17
Q

What is the primary drug for Stronguyloides Stercoralis Tx?

A

Ivermectin

18
Q

What is the primary drug for Trichuris Trichiura Tx?

A

Mebendazole

19
Q

What are the primary drugs for Enterobius Vermicularis Tx?

A

Albendazole, Mebendazole, Pyrantel Pamoate

20
Q

What is the MOA of Albendazole, Mebendazole, and Thiabendazole?

A

Inhibit microtubule synthesis

21
Q

What is the MOA of Ivermectin?

A

Stimulates GABA in peripheral neurons

22
Q

What is the MOA of Pyrantel Pamoate?

A

Stimulates Ach and inhibits AchE at NMJ

23
Q

What is excreted in the feces from Schistosomas?

A

Eggs

24
Q

What is excreted in the feces from Taenia Solium/Saginata?

A

Proglottids

25
Q

What is excreted in the feces from Diphyllobothrium Latum?

A

Proglottids

26
Q

What drug is used to Tx Schistosomas?

A

Praziquantel

27
Q

What drug is used to Tx Taenia Solium/Saginata?

A

Praziquantel

28
Q

What drug is used to Tx Diphyllobothrium Latum?

A

Niclosamide

29
Q

What drug is used to Tx Echinococcus Granulosus?

A

Praziquantel

30
Q

What is the MOA of Praziquantel?

A

Increase Ca permeability of cell membranes causing paraylsis