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Pharm Unit 6: Misc > IBD meds > Flashcards

IBD meds Flashcards

1
Q

Alosetron (Lotronex) Misc

A

FDA approval recently withdrawn

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2
Q

Sulfasalazine (Azulfidine) Class

A

Anti-inflammatory

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3
Q

Olsalazine (Dipentum) Class

A

Anti-inflammatory

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4
Q

Mesalamine (Pentasa) Class

A

Anti-inflammatory

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5
Q

Prednisone (Decadron) Class

A

Corticosteroid

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6
Q

Azathioprine (Imuran) Class

A

Immunosupressive

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7
Q

Cyclosporine (Sandimmune) Class

A

Immunosupressive

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8
Q

Infliximab (Remicade) Class

A

MAb Immunosupressive

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9
Q

Sulfasalazine (Azulfidine) MOA

A

Work from lumen to reduce inflammation

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10
Q

Olsalazine (Dipentum) MOA

A

Work from lumen to reduce inflammation; 5-ASA dimer

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11
Q

Mesalamine (Pentasa) MOA

A

Work from lumen to reduce inflammation

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12
Q

Azathioprine (Imuran) MOA

A

Purine antimetabolite; interferes with DNA synthesis

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13
Q

Cyclosporine (Sandimmune) MOA

A

Suppresses T helper and T suppressor lymphocytes

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14
Q

Infliximab (Remicade) MOA

A

Binds and neutralizes TNFa

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15
Q

Sulfasalazine (Azulfidine) Therapies

A

Acute IBD (UC)

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16
Q

Olsalazine (Dipentum) Therapies

A

Acute IBD (UC)

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17
Q

Mesalamine (Pentasa) Therapies

A

Acute IBD (UC)

18
Q

Prednisone (Decadron) Therapies

A

Acute IBD, chronic IBD

19
Q

Azathioprine (Imuran) Therapies

A

Chronic IBD

20
Q

Cyclosporine (Sandimmune) Therapies

A

Chronic IBD

21
Q

Infliximab (Remicade) Therapies

A

Chronic IBD

22
Q

Sulfasalazine (Azulfidine) SE

A

Toxicity coming from systemic absorption of sulfapyridine

23
Q

Olsalazine (Dipentum) SE

A

Less toxicity than sulfasalzine

24
Q

Sulfasalazine (Azulfidine) Misc

A

Sulfapyridine conjugated to 5-ASA to prevent its degradation, improve its absorption; bond broken in large bowel by bacteria

25
Q

Olsalazine (Dipentum) Misc

A

Broken down into bowel by bacteria into 2 moleules of 5-ASA

26
Q

Mesalamine (Pentasa) Misc

A

Delayed release 5-ASA, for terminal ileum, colon

27
Q

Prednisone (Decadron) Misc

A

Can be given systemically or as enemas

28
Q

Dicyclomine HCl (Bentyl) Class

A

Anticholinergic (antispasmodic)

29
Q

Hyoscyamine sulfate (Levsin) Class

A

Anticholinergic (antispasmodic)

30
Q

Alosetron (Lotronex) Class

A

Serotonergic antagonist

31
Q

Tegaserod maleate (Zelnorm) Class

A

Serotonergic agonist

32
Q

Dicyclomine HCl (Bentyl) MOA

A

Blocks cholinergic action

33
Q

Hyoscyamine sulfate (Levsin) MOA

A

Blocks cholinergic action

34
Q

Alosetron (Lotronex) MOA

A

Blocks 5HT3

35
Q

Tegaserod maleate (Zelnorm) MOA

A

Hits 5HT4

36
Q

Dicyclomine HCl (Bentyl) THerapies

A

Reduce spasm in irritable bowel syndrome

37
Q

Hyoscyamine sulfate (Levsin) Therapies

A

Reduce spasm in irritable bowel syndrome

38
Q

Alosetron (Lotronex) Therapies

A

Diarrhea in irritable bowel syndrome

39
Q

Tegaserod maleate (Zelnorm) Therapies

A

Constipation in irritable bowel syndrome

40
Q

Alosetron (Lotronex) SE

A

Ischemic bowel, Constipation

41
Q

Tegaserod maleate (Zelnorm) Misc

A

FDA approval recently withdrawn

42
Q

Alosetron (Lotronex) Misc

A

FDA approval recently withdrawn

Pharm Unit 6: Misc (9 decks)

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