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Pharm Unit 6: Misc > Anti-Emetic Drugs > Flashcards

Anti-Emetic Drugs Flashcards

1
Q

Odansetron (Zofran) Misc

A

Very safe for vomiting of any type (including drug-induced); can even be given to 6 month-old

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2
Q

Prochlorperazine (Compazine) Class

A

Phenothiazines (neuroleptic class)

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3
Q

Promethazine (Phenergan) Class

A

Phenothiazines (neuroleptic class)

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4
Q

Trimethobenzamide (Tigan) Class

A

Benzamide derivitive

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5
Q

Odansetron (Zofran) Class

A

Serotonin (5HT3) receptor antagonists

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6
Q

Granesitron (Kytril) Class

A

Serotonin (5HT3) receptor antagonists

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7
Q

Dolasetron (Anzemet) Class

A

Serotonin (5HT3) receptor antagonists

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8
Q

Prochlorperazine (Compazine) MOA

A

Probable CNS interaction with dopaminergic receptor-antagonist (leading to reduction of stimulation in the CRTZ in the medulla)

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9
Q

Promethazine (Phenergan) MOA

A

Antihistaminic (H1 receptor), anticholinergic

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10
Q

Trimethobenzamide (Tigan) MOA

A

Unknown effect on CRTZ

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11
Q

Tetrahydrocannabinol (Nabilone) MOA

A

Suppresses CRTZ, probably by anticholinergic mechanism

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12
Q

Odansetron (Zofran) MOA

A

Blocks serotonin at 5HT3 receptor (in central CRTZ)

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13
Q

Granesitron (Kytril) MOA

A

Blocks serotonin at 5HT3 receptor (in central CRTZ)

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14
Q

Dolasetron (Anzemet) MOA

A

Blocks serotonin at 5HT3 receptor (in central CRTZ)

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15
Q

Prochlorperazine (Compazine) Therapies

A

Anti-emetic

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16
Q

Promethazine (Phenergan) Therapies

A

Anti-emetic

17
Q

Trimethobenzamide (Tigan) Therapies

A

Anti-emetic

18
Q

Tetrahydrocannabinol (Nabilone) Therapies

A

Anti-emetic

19
Q

Odansetron (Zofran) Therapies

A

Anti-emetic

20
Q

Granesitron (Kytril) Therapies

A

Anti-emetic

21
Q

Dolasetron (Anzemet) Therapies

A

Anti-emetic

22
Q

Prochlorperazine (Compazine) SE

A

Largely extra-pyramidal (torticollis!)

23
Q

Promethazine (Phenergan) SE

A

Somnolence (especially in the elderly)

24
Q

Trimethobenzamide (Tigan) SE

A

Low-side effect profile; possible extra-pyramidal symptoms, but not so severe

25
Q

Tetrahydrocannabinol (Nabilone) SE

26
Q

Odansetron (Zofran) SE

A

Headache, dizziness, somnolence

27
Q

Granesitron (Kytril) SE

A

Headache, dizziness, somnolence

28
Q

Dolasetron (Anzemet) SE

A

Headache, dizziness, somnolence

29
Q

Trimethobenzamide (Tigan) Misc

A

Not used much

30
Q

Tetrahydrocannabinol (Nabilone) Misc

A

Now often administered in pill form

31
Q

Odansetron (Zofran) Misc

A

Very safe for vomiting of any type (including drug-induced); can even be given to 6 month-old

Pharm Unit 6: Misc (9 decks)

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