IBD

Question 1

Ulcerative colitis age?

Answer 1

20-40yrs

females

Question 2

presentation in ulcerative colitis?

Answer 2

bloody diarrohea
abdo pain
weight loss

Question 3

type of inflammation in ulcerative and Crohns?

Answer 3

continuous ulcerative (doesn't skip parts)
crohns is patchy

Question 4

Ulcerative colitis severe attack markers? (6)

Answer 4

>6 blood stools AND fever
tachycardia
^CRP
Anaemia
Low albumin
Thrombocytosis (high platelet)

Question 5

Crohn’s disease age?

Answer 5

two peaks

early adulthood 20-40
over 60

Question 6

clinical features?

Answer 6

does depend on region involved

diarrhoea
abdo pain
malaise lethargy
weight loss & anorexia
malabsorption

Question 7

Crohn’s disease investigations?

Answer 7

bloods (high ESR+CRP+Platelet+WCC)(low Hb+albumin)

detection of calprotectin in stool

Question 8

What is found in Crohn’s that isn’t in ulcerative?

Answer 8

crohns has fistulae and peri-anal disease

Question 9

outpatient treatment?

Answer 9

5ASA (mesalazine) induction of remission + maintenance
steroids
immunosuppression

Question 10

hospital treatment? (5)

Answer 10

steroids (prednisolone) TAPERING REDUCTION
aminosalicylates
thiopurines (azathioprine - induct remission)
elemental feeding (AA diet more effective children)
antibiotics (metronidazole)

Question 11

surgery for severe colitis?

Answer 11

total colectomy

pouch surgery

Question 12

step-up approach (5)?

Answer 12

5ASA
prednisolone or budesonide
immunomodulators (AZA)
Biologic Agents
Surgery