Hypo/HyperTHYROIDISM

Question 1

What 3 things should be measured with thryoidisms

Answer 1

TSH
T4 (free)
T3 (free)

Question 2

What are signs of Primary Overt Hypothyroidism?

Answer 2

High TSH
Low fT4
Low/normal fT3

Question 3

What are signs of Primary subclinical hypothyroidism?

Answer 3

High TSH
normal fT4
normal fT3

Question 4

What are signs of Secondary Hypothyroidism?

Answer 4

Low/normal TSH
Low fT4
Low/normal fT3

Question 5

What is Myxoedema?

Answer 5

Severe hypothyroidism
e.g. myxoedema coma
OR
accumulation of hydrophilic mucopolysaccharides in dermis and other tissues = Pretibial myxoedema (seen in GRAVES disease i.e. thyrotoxicosis

Question 6

What is chronic thyroiditis (Hashimoto’s thyroiditis)?

Answer 6

hereditary biosynthetic defects
Maternally transmitted (antithroid agents, iodides)

Question 7

What are some signs and symptoms of hypothyroidism?

Answer 7

coarse/sparse hair
Dull expressionless face
Periorbital puffiness
Pale cool skin that feels doughy to touch
Vitiligo may be present
Hypercarotenaemia
Cold intolerance
Pitting oedema

Question 8

What cardiac signs are associated with hypothyroidisms?

Answer 8

Reduced heart rate
Cardiac dilation
Pericardial effusion
Worsening of heart failure

Question 9

What are signs and symptoms of hyperthyroidism?

Answer 9

Palpatations
Atrial fibrillation
Cardiac failure
Tremor, sweating