Calcium Homeostasis

Question 1

What are treatments for acute hypocalcaemia?

Answer 1

IV calcium gluconate
10ml, 10% over 10 mins
(in 50ml saline or dextrose)
Infusion - (10ml in 100ml infusate at 50ml/h

Question 2

What is a type of hypoparathyroidism?

Answer 2

DiGeorge syndrome

Question 3

What are causes of hypocalcemia?

Answer 3

Hypoparathyroidism
Vit D deficiency (osteomalacia, rickets)
Chronic renal failure
+ others

Question 4

Describe hypomagnasaemia

Answer 4

Calcium release fro cells is dependant on magnesium
In magnesium deficiency intracellular calcium is high
PTH release is inhibited
Skeletal and muscle receptors less sensitive to PTH
If low replace with calcium and magnesium

Question 5

What are causes of hypomagnasaemia

Answer 5

Alcohol
Drugs - thiazide, PPI
GI illness
Pancreatitis
Malabsorption