Hypertension Flashcards

1
Q

In what 3 ways does Na sensitivity play a role in hypertension

A

correlates with:
–Low plasma renin activity (reflecting volume overload)
–Decreased capacity of RAAS
–Insulin resistance

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2
Q

What is potassium compared to sodium role in BP

A

Inversely affects BP

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3
Q

Effect of K supplementation on BP is more pr o n o u n c e d i n

A

African Americans and salt sensitive individuals

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4
Q

3 mechanism by which K lowers BP

A

Natiuresis (sodium excretion)

Reduction of urinary excretion of Ca and Mg

Increase in smooth muscle relaxation

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5
Q

Calcium may exert what effect on BP and how?

A

a beneficial effect on blood pressure through its interaction with sodium (although evidence weak)

Increased calcium leads to increased natiuresis

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6
Q

Magnesium is inversely associated with blood pressure by evidence for a causal relationship is weak

A

K

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7
Q

What 3 side effects is low magnesium associated with

A

increased smooth muscle tension

vasospasms

high BP

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8
Q

What is the only cation associated with increase BP

A

Na

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9
Q

3 characteristics of DASH diet

A

Physical activity

Alcohol restriction

Weight loss

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10
Q

6 DASH diet protocols

A
–3 g Na 
–4,500 mg K 
–8-10 servings fruits and vegetables 
–2-3 servings low fat dairy 
–Nuts, legumes, seeds 
–Limit red meat, fats, sugar-sweetened foods and beverages
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11
Q

Na overconsumption may be associated with

A

increased BP

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