Hypertension Flashcards
In what 3 ways does Na sensitivity play a role in hypertension
correlates with:
–Low plasma renin activity (reflecting volume overload)
–Decreased capacity of RAAS
–Insulin resistance
What is potassium compared to sodium role in BP
Inversely affects BP
Effect of K supplementation on BP is more pr o n o u n c e d i n
African Americans and salt sensitive individuals
3 mechanism by which K lowers BP
Natiuresis (sodium excretion)
Reduction of urinary excretion of Ca and Mg
Increase in smooth muscle relaxation
Calcium may exert what effect on BP and how?
a beneficial effect on blood pressure through its interaction with sodium (although evidence weak)
Increased calcium leads to increased natiuresis
Magnesium is inversely associated with blood pressure by evidence for a causal relationship is weak
K
What 3 side effects is low magnesium associated with
increased smooth muscle tension
vasospasms
high BP
What is the only cation associated with increase BP
Na
3 characteristics of DASH diet
Physical activity
Alcohol restriction
Weight loss
6 DASH diet protocols
–3 g Na –4,500 mg K –8-10 servings fruits and vegetables –2-3 servings low fat dairy –Nuts, legumes, seeds –Limit red meat, fats, sugar-sweetened foods and beverages
Na overconsumption may be associated with
increased BP