Hypertension Flashcards

1
Q

Hypertension can be ?

A
  1. Chronic
  2. Acute
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2
Q

Chronic hypertension is

A
  • consistent elevation of systemic arterial blood pressure
  • > 130/90 mmHg
  • most common primary diagnosis or condition in the US
  • risk increase with age
  • diabetics increases risk of chronic hypertension
  • increased risk for MI, stroke, and kidney disease
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3
Q

Acute hypertension is

cause?

A
  • > 180/120
  • also called magilant hypertension
  • lead to life treatning organ damage if not treated

Cause
- uncontrolled severe primary hypertension
- pregnancy
- medication rxn
- alcohol withdrawal
- cocaine or amphetamine use

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4
Q

Hypertension is classified as

A
  1. Primary: cause is unknown so it is hard to treat
    - 92-95% cases
    - has many contributing factors like genetics, neurohormonal, and environmental
  2. Secondary: cause is known so it is easy to treat
    - caused by systemic disease process that raises peripheral vascular resistance or cardiac output
    - 5-10% cases
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5
Q

Risk factors for hypertension

A

Non modifiable= genetics …family history
- age
- gender
- diabetics type 1
Modifiable: smoking
- weight
- stress
- hypertension
- diets
- cholesterol
- physical motility
- diabetics type 2

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6
Q

Clinical manifestation of hypertension is

A
  • asymptomatic until an organ is affected
  • dizziness
  • fatigue
  • palpitations
  • angina
  • dyspnea
  • headache
  • nosebleeds
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7
Q

complications of hypertension

A

causes organ damage
- heart- heart failure
- kidneys—renal failure
brain—-stroke and MI
eyes—-blindness
blood— elevated blood sugar level

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8
Q

Classification of hypertension

A

Normal ===< 120/80
elevated ==120-129/80
stage 1===130-139/80-89
stage 2===>140/90
hypertensive crisis ===>180/120

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9
Q

Common Artery Disease

A
  • vascular disorder that narrows or occludes the coronary arteries leading to myocardial ischemia
  • atherosclerosis is the common cause
  • has same risk factors as atherosclerosis and hypertension
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10
Q

Non- traditional risk factors of common artery disease

A
  • marker of inflammation and thrombosis
  • adipokines
  • chronic kidney disease
  • air pollution and ionization radiation
  • certain medications
  • microbiome
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11
Q

Myocardial ischemia is?

Clinical manifestation

A
  • local, temporary deprivation of oxygen in the blood vessels

Clinical manifestation
- angina= chest pain

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12
Q

Myocardial ischemia can be classified as

A
  • stable angina pectorais
  • Unstable ( acute coronary syndrome)
  • prinzmetal angina
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13
Q

Stable angina pectrolasi

A
  • caused by chronic coronary obstruction
  • recurrent, intermentioned, “ predictable chest pain”
  • relived with rest
  • pain is associated with physical activity, stress, emotional disorder
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14
Q

Unstable ( Acute coronary syndrome)

Clinical manifestation ?

A
  • results from reversable MI
  • precursor for inflammation
  • often caused by unstable or liable plaque or thrombi
  • new onset that occurs with cerebral palsy that occurs at rest or with pattern that changes from patient chronic stable angina pattern

-clinical manifestation
- sudden severe chest pain, may radiate to jaw, down left shoulder and to the back
- chest heaviness, pressure” elephant sitting on chest”
- nausea, vomiting
- cool, clammy, diaphoretic skin
- dyspnea
- high HR and BP initially

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15
Q

Prinzmetal angina

A
  • caused by coronary artery spasm caused by increased intercellular calcium that leads to MI
  • occur when resting and when exposed to cold
  • triggered by smoking, alcohol consumption and cocaine use
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16
Q

Myocardial infarction

A
  • caused by occlusions of blood flow through coronary artery by thrombus that results from platelet aggregation.
  • causes irreversible damage to heart muscle
  • two types
    1. STEMI
    2. NSTEMI
17
Q

STEMI

A
  • ST elevation caused by occlusive thrombi
  • elevation on 12 lead EKG— tombstone
    highest risk for mortality and severe complications
18
Q

NSTEMI

A
  • ST deprivation and T wave inversion
  • ## caused by non-occlusive thrombus
19
Q

Serum cardiac biomarkers

A
  • troponin T and troponin I
    - most specific indicators of MI
    - levels increase after the inset of MI
    - return to base line over 10 to 14 days
    creatine kinase
  • myoglobin
  • usually serial cardiac enzymes will be drawn every 6hrs three times
20
Q

Post MI changes

A

ventricular remodeling after acute infraction
- initial infraction
- expansion of infraction
- global remodeling