Hypersensitivity Flashcards
Activation of immune system causes in a person
Inflammation causing pain and discomfort,, toxic molecules produced can also cause tissue damage which can be fatal
Antigen
Molecule that can be recognised by an antibody or the adaptive immune system
What do all hypersensitivity reactions require
The immune system to have become pre sensitised and so have existing adaptive immunological memory
Which antibodies are y shaped
E,G,D
Which antibody is a dimer
A
Which antibody is a pentamer
M
Where is j chain seen in antibodies
Joining two monomers
Th1
Type 1 helper cells
Cd4 helper T cells functiom
Activation of macrophages b cells and other cells
Memory
Cd8 T cell function
Killing infected target cells and macrophage activation
Other names of type 1 hypersensitivity
Immediate or anaphylactic hypersensitivity
What is type 1 hypersensitivity
An allergic reaction provoked by reexposure to an allergen (an antigen)
Examples of type 1 hypersensitivity diseases
Asthma, allergic rhinitis, urticaria, atopic dermatitis
What mediated type 1 hypersensitivity reeactions
Antigen specific IgE antibodies
When do none allergic individuals make IgE antibodies
Response to parasitic infection or very potent venoms
