Human Virology part two.. Flashcards
Breifly list some types of herpes viruses
varicella zoster/shingles
cytomegolavirus (CMV)
herpes simplex 1/2
epstien barr virus (EBV)
what is the structure of a herpes virus?
a) heart
b) square
c) octagon
d) diamond
diamond
once u have herpes its usually latent with recurrent infections T or F
T
Varicella Zoster:
highly infectios and contagious (airborne) during chicken box
could come back in adult hood as shingles and its still contagious then to lil bebes
what is CMV?
cytomegolavirus is a herpes virus thats activated in immunosuppressed people (ppl with aids)
its the leading cause of blindness in ppl with aids
Herpes simplex virus 2 is presented orally: TRUE OR FALSE
FALSE - herpes 1 is oral herpes 2 is genital
what is EBV and what can it lead to? why is it better to have ______ when ur little and not older
Epstien Barr Virus! it can lead to infectious mono - better to have it when your little because its very agressive and reaction is much stronger in your adult life
EBV can be really serious, why?
results in a large amount of lymphocytes that can be suggestive of something alot more severe = leukemias
what are two herpes viruses as oncogenic viruses?
EBV & Herpes Virus 8
What malignancies has EBV been linked to?
Burkitts lymphoma - b cells
nasopharyngeal carcinoma
lymphomas in immuno suppresion
+EBV is an opportunistic virus that normally exists in our body but only causes disease when our immune system is down (aids, cancer, sick ppl yo)
What is herpes 8 virus linked to?
Kaposi’s Sarcoma - common with aids
what are some other oncogenic viruses?
HPV: cervical carcinoma
Heb b/C: a retrovirus - infects the liver and causes cancer; HEP b cells are constantly being killed by the immune system, and our liver is so fast at regenerating that it casues mustations = cancer
What are the effects of the virus on the host?
inhibits dna and rna syntehsis: virus is using all the mechanisms so the host cant
makes new viral genome and protiens: cell death
Abnormal protiens
Indefinte growth
What are the consequences of a viral infection?
asymptomatic and persistent and chronic infection
increase spread of infection to other people (asymptomatic)
suffering followed by recover - not all but mostly children
congenital disease - neonatal rubella
contributing factor in disease: schizo’s with rubella, autoimmune disease, and MS
contributing factors to cancers