Human development II Flashcards

exam 2

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1
Q

oocyte atresia

A

before birth there is a major decline and it keeps declining after birt h

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2
Q

fertilization may occur elsewhere in the _________, but not in the _______

A

fertilization may occur elsewhere in the fallopian tube, but not in the uterus

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3
Q

fertilization begins with contact between

A

sperm and secondary oocyte plasma membrane

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4
Q

fertilization ends with intermingling of maternal and paternal chromosomes at

A

metaphase of the first zygotic division approx. 24 hours later

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5
Q

oocyte is swept into the

A

Fallopian tube

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6
Q

if an oocyte is fertilized, the __________ secretes even higher levels of progesterone

A

corpus luteum

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7
Q

in the female reproductive tract, muscular contractions are stimulated by

A

PGE2 in the semen

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8
Q

sperm concentration is

A

100 million/ml

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9
Q

[sperm] counts lower than _____ associated with sub-infertility

A

10 million/ml

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10
Q

sperm capacitation

A

freshly ejaculated sperm are unable to fertilize and require capacitation

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11
Q

acrosome reaction is induced by

A

receptor fr ZP3, one of the zona pellucida glycoproteins

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12
Q

acrosome reaction is induced by

A

receptor for ZP3, one of the zona pellucida glycoproteins

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13
Q

ACE causes

A

the release of enzyme that break down the matrix and permit sperm penetration through the follicular cells and the zoma pellucida

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14
Q

ACE causes

A

the release of enzyme that break down the matrix and permit sperm penetration through the follicular cells and the zoma pellucida

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15
Q

receptor for ZP3 determines

A

specificiation

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16
Q

Fusion

A

oocyte now completes meiosis II and becomes a mature oocyte

17
Q

Plasma membranes sof the oocyte and sperm fuse– is the start of

A

fertilization

18
Q

sperm-oocyte membrane fusion triggers rapid and massive

A

exocytosis of the cortical contents

19
Q

produces the block to polyspermy

A

cortical reaction

20
Q

lysosome derivative

A

cortical granule

21
Q

two mechanisms of the cortical rxn

A
  • crosslinking

- degrading ZP3

22
Q

cortiocal rxn is initiated by

A

calcium

23
Q

calcium wave requires

A

frequency and amplitude

24
Q

the pronuclei fuse and all

A

chromosome replicate

25
Q

after chromosome replication occurs and fertilization is over… how long did it took?

A

about 24 hr

26
Q

results of fertilization, stimulates the secondary oocyte to complete

A

meiosis II

27
Q

results of fertilization, restores the

A

normal amount of chromosome #

28
Q

triploids account for

A

20% of chromosomally-abnormal spontaneous abortions

29
Q

polyspermy results in

A

triploid zygote

30
Q

miscarriages fraction

A

1/3