Human Development and Aging Flashcards
What is embryogenesis?
Events in development leading up to the embryo
The preembryonic stage is___
the first 16 days after fertilization
What is the fertilization window?
egg must be fertilized within 12-24 hours of ovulation
What is sperm capacitation?
the process that migrating sperm must undergo to make egg penetration possible
What are the two important events that occur during capacitation?
- Female fluids leech cholesterol from sperm
- sperm becomes permiable to to Ca2+ increasing powerful flagella movements
How long is sperm viable for after ejaculation?
6 days
What reaction does sperm undergo when it encounters the egg?
An acrosomal reaction
What is a acrosomal reaction?
The exocytosis of the acrosome causing the release of enzymes needed to penetrate the egg
Once acrsomoal enzymes clear a path through the granulosa cells the next step is?
-sperm binds to the zona pellucida releasing more enzymes to help it to contact the egg
Once the sperm contacts the egg?
The egg destroys the sperms mitochondria so only the head enters
Fertilization is a combination of ___
The haploid set from the egg and spem combind
When the two haploid sets combine what is the produce?
a diploid. Fertilization is complete
What is polyspermy?
Fertilization of an egg by two or more sperm
What two mechanisms prevent polyspermy?
- Fast block-when sperm binds it opens Na+ channels causing depolarization preventing additional binding
- slow block-Penetration by sperm causes inflow of Ca2+ causing a swell of fluid beneth the zona pellucida pushing the rest of the sperm away
What step occurs after fertilization?
-The secondary oocyte completes meiosis II
What becomes of the egg and sperms nuclei after fertilization?
- The egg discards one chromatid from each chromosome
- the sperm and egg swell to become pronuclei
- pronucli rupture and mix into a single diploid set
Once a diploid set is formed the egg is now called a ___ and is ready for___
Zygote ready for mitotic division
____ of all embros die in the first trimester. Why?
- more than 50%
- Conceptus is most vulnerable at this stage and precautions may not be taken because pregnancy may not have been noticed yet
What developments occur in the second trimester?
- Most organs complete development
- Distinct human form
- Possible to survive if born
What occurs during the thrid trimester
- Fetus growth is rapid
- organs can support life
- birth occurs at end of third trimester
When is a fetus considered mature?
35 weeks and 5.5 pounds
What are the three major processes during the preembryonic stage?
- Cleavage
- Implantation
- Embryogenesis
What is cleavage?
mitotic divisions in the first 3 days after fertilization
What is implantation?
The zygote implants itself into the endometrium
What is embryogenesis?
the arrangement of the three primary germ layers
How many cells are produced during cleavage?
how long is the process of cleavage?
about 100 cells in about 72 hours
The end result of cleavage is called the___. How long does it rest in the uterus until implantation?
Morula?
4-5 days
The morula becomes a blastocyst after___
The zona pellucida disintegrates and releases the conceptus
What is the internal cavity of the blastocyst?
The blastocel
What is the inner mass within the blastocel?
The embryoblast