Female Reproductive System Flashcards
What are the three stages of female puberty? TPM
- Thelarche-Brest development
- Pubarche- Pubic and axillary hairs
- Menarche-First menstral period
when do females begin ovulating regularly?
about a year after menarche
Define Climacteric.
What follows it
(period of decreased hormone secretion)
followed by menopause
When does climacteric begin?
When a female has about 1000 follicles left
What is menopause and when is it official?
A complete cessation of menstrual cycles official after no menstrual cycle for a year
What is the reproductive cycle?(Female)
the sequence of events from fertilization to giving birth and returning to pertility
What is the sexual cycle? (Fmale)
events that recur every month when
pregnancy does not intervene
What are the two cycles within the sexual cycle?
The ovarian cycle and the menstral cycle
What is the ovarian cycle?
The production of eggs (oogenesis) and the production of follicles around it (Folliculogenesis)
What are the three main phases of Oogenesis?
- Embyonic development
- Resuming of development in adolescence
- Oocyte is ovulated
What occurs during Embryonic development in oogenesis?
- Germ cells differentiate into oogonia and multiply via mitosis
- Begin meitosis but pause in the first round as a primary oocyte.
What occurs onces egg development resumes during oogenesis?
- Around 24 oocytes a month are stimulated by FSH to complete meiosis 1.
- secondary oocyte continues meiosis until metaphase II
What are the final products of primary oocyte meiosis 1?
- A secondary oocyte
- First polar body
What occurs during secondary oocyte ovulation?
- If it is not fertilized it dies
- if fertilized it completes meiosis II and casts off second polar body
What occurs during Folliculogenesis Embryonic development
- Primordial follicles form around primary oocytes(paused in meiosis I)
- Simple squamish in cortex
What point do Recruted primordial follicles become primary follicles?
140 days into the cycle
What are the characteristics of a primary follicle?
- Contains a secondary oocyte
- Single layer of cuboidal cells
- Develops FSH receptors
What controls the growth of primary follicles?
FSH
When are secondary follicles formed?
170 days into cycle
about 6 menstrual cycles from ovulation
What are the three main characteristics of a Secondary follicle? MZT
- Multi-layered granulosa cells
- Zona pellucida layer of gel forms around the oocyte
- Theca folliculi connective tissue forms a husk around the follicle
What are the two layers of the theca folliculi?
- The theca externa
- the theca interna
What is the function of the theca folliculi?
- outter layer delivers nutrients, hormones, and cholesterol
- inner layer produces androgens from the delivered cholesterol(makes estrogen)
When do secondary follicles become tertiary follicles?
60 days before ovulation
What are the characteristics of tertiary follicles?
- Large antrums of follicular fluid
- presence of a cumulus oophorus
What is the function of the cumulus oophorus?
It is a mound that surrounds the oocyte and secures it to pace
What is the function of the corona radiata and what follicle stage is it found in?
- Inner layer of the cumulus
- Forms a protective layer similar to the blood-testis barrier
When do mature (graafian) follicles form?
20 days before ovulation they begin to captur FSH and grow
-normally only one tertuary follicle becomes mature
What is the average length of the sexual cycle?
28 days
What is the basic hierarchy of hormonal control of the sexual cycle
– Hypothalamus> pituitary >ovaries >uterus
The first two weeks of the sexual cycle are called the ____ because…
-follicular phase
Follicles are growing a one becomes mature
What occurs in the uterus during the follicular phase of the sexual cycle?
Menstruation during the first 3-5 days
What occurs on day 14 of the sexual cycle?
ovulation
The phase of the sexual cycle after ovulation is called?
The luteal phase
What occurs during the luteal phase of the sexual cycle?
- The graafian follicle becomes a corpus luteum
- Corpus luteum stimulates the secretion and thickening of the endometrium
What occurs during the luteal phase of the sexual cycle if pregnancy does not occur?
- The endometrium breaks down due to decreased stimulation from Corpus Luteum
- menstruation begins and the cycle resets
What occurs in the ovarian cycle during the follicular phase?
- FSH stimulates follicle growth
- FSH stimulates production of estradiol in the follicles and a dominate one is picked
- Dominate follicle up-regulates receptors for FSH, LH, and estradiol
- Other follicles die
How does the dominant follicle survive when others die
It developed extra receptors for hormones as well as a rich blood supply.
What hormone does estradiol inhibit to cause the death of the non dominant follicles?
It inhibits GnRH which in tern inhibits FSH causing those without extra receptors to atrophy
What two hormones spike to induce ovulation?
LH and FSH
What events occur leading up to ovulation that are induced by LH
- Primary oocyte matures by completing meiosis 1 producing secondary oocyte
- Follicle swells
- WBC’s weeken the wall of the follicle
- Ovulation occurs
What becomes of the graafian follicle after ovulation?
It becomes a corpus luteum
What is the function of the corpus luteum?
-Secretes estrogen and estradiol under the control of LH
What is the function of the estradiol produced by the corpus luteum?
to prepare the uterus for pregancy
What caused the corpus luteum to shrink and stop producing hormones?
Estradiol and progesterone inhibit FSH and LH
- The LH was maintaining the Corp. Lut.
Once the corpus luteum is fully involuted it becomes a ___
corpus albicans
What is the menstrual cycle?
Buildup of endometrium during most of the sexual cycle, followed
by its breakdown and vaginal discharge
What are the four phases of the menstrual cycle?
- Proliferative
- Secretory
- Premenstrual
- Menstrual