HTN Tx

Question 1

Hydralizine MOA

Answer 1

artery vasodilator

Question 2

hydralizine SE

Answer 2

SLE, edema, reflex tachy

Question 3

hydralazine can be used in pregnancy?

Answer 3

yes

Question 4

nitroprusside MOA

Answer 4

vein and artery vasodilation, DOC for HTN emergency

Question 5

what do take with nitroprusside and why

Answer 5

nitrites and thiosulfate to decrease cyanide toxicity

Question 6

Minoxidil and Diazoxide MOA

Answer 6

open ATP dep. K channel in arterioles and beta cells of pancrease, leads to hyperpolarization and thus arteriolar vasodilation

Question 7

Diazoxide uses

Answer 7

HTN emergencies

Question 8

Minoxidil uses

Answer 8

severe HTN, baldness (topical use)

Question 9

Minoxidil and Diazoxide SE

Answer 9

low insulin release causing hyperglycemia, hypertrichosis (minoxidil), edema, reflex tachy

Question 10

CCB drugs

Answer 10

verapamil, diltiazem, dipine drugs

Question 11

CCB drugs with more cardiac action

Answer 11

verapanil and diltiazen

Question 12

CCB uses

Answer 12

HTN, vasospastic angina

Question 13

CCB SE

Answer 13

reflex tachy (dipines mostly), gingival hyperplasia, constipation (verapamil)

Question 14

ACE inhibitors

Answer 14

pril drugs

Question 15

AT-1 receptor blockers

Answer 15

rtan drugs

Question 16

ACE and ARB CI

Answer 16

renal actery stenosis due to causation of renal failure acutely, pregnancy

Question 17

captopril can cause

Answer 17

angioedema