class III anti arrhytmatcis Flashcards
1
Q
MOA of this class
A
slow phase 3, K channel blocker
2
Q
Drugs in this class
A
Amiodarone, sotalol
3
Q
Amiodarone mimics
A
class I, II, III, IV
4
Q
Amiodarone uses
A
any arrythmia
5
Q
Amiodarone problems
A
half life is >80 days, its so slow due to high tissue protein binding
6
Q
Amiodarone SE
A
pulm. fibrosis, blue pgment of skin (smurf skin), phototox, corneal deposits, hepatic necrosis, Thyroid dysfxn(the IOD in name)
7
Q
Sotalol uses
A
life threatening V-arrhytmia
8
Q
Sotalol targets
A
class III use and B1 blocker