HPB Flashcards

1
Q

def de HPB

A

agrandamiento benigno de la prostata por proliferación de estroma y epitelio

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2
Q

Zona de HPB

A

transicional

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3
Q

Principal factor de la HPB

A

andrógenos

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4
Q

hormona que convierte a la testosterona en DHT

A

alfa5 reductasa

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5
Q

tipos de alfa 5 reductos y farma

A

tipo 1- dutasterida
tipo 2 - dutasterida y finasterida

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6
Q

ubicación de las enzima 5alfa reductasa

A

tipo 1 extra prostatica
tipo 2 Prostática

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7
Q

prevalecia de HPB en <60 años

A

50%

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8
Q

Fisiopatología de HPB

A

1) HP
2) obstrucción
3) alteración del detrusor
4) LUTS

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9
Q

Cambios ocasionados por la obstrucción

A

Inestabilidad del detrusor o disminución de complianza
Trabeculación vesical
Colágeno en detrusor

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10
Q

FR

A

obesidad
Farma - alfa simpaticomimeticos, antihistaminicum, antidepre

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11
Q

Complicaciones de la HPB

A

retención de orina aguda
Hematuria
Incontinencia
trabeculaciones vesicales
Hiperazoemia
IVU
litiasis

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12
Q

IPSS

A

PUDINTF
leve 0-7
mod 8-19
severo 20-35

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13
Q

PUDINTF

A

Pujo
Urgencia
Dis de fuerza
Intermitencia
Nicturia
Tenesmo
Frecuencia

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14
Q

Dx diferenciales y diferencias en US

A

Prostatitis - hipervascularización, dolor al comprimir
HPB - aumento de volumen, poca microvascularización
C. P - perdida de morfo

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15
Q

Evaluación de la obstrucción

A

Uroflujometria

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16
Q

Tx de HPB

A

5alfa redactada - finasteride o dutasterida
alfa bloqueador - tamsulosina

17
Q

tx qx indicaciones absolutas

A

Hematuria
Lesión renal
Retención orinaria
IVUs recurrentes
no resp a tx

18
Q

IPSS <7 tx

A

observar o farma si sintomas

19
Q

IPSS >7

A

farma o cx