Host Interactions

Question 1

<p>Substrate of A-B toxins

| </p>

Answer 1

<p>NAD </p>

Question 2

<p>Diphtheria toxin binds to </p>

Answer 2

<p>heparin binding epidermal growth factor EGF </p>

Question 3

<p>Exotoxin A is produced by...</p>

Answer 3

<p>P. aeruginosa </p>

Question 4

<p>ExoA target</p>

Answer 4

<p>alpha 2 macroglobulin </p>

Question 5

<p>Cholera toxin target</p>

Answer 5

<p>Gs alpha regulatory domain of adenylate cyclase </p>

Question 6

<p>Anthrax toxin components </p>

Answer 6

Edema factor - calmodulin dependent adenylylcyclase

Lethal factor - Zn2+ metalloprotease

Question 7

Tetanus toxin action

Answer 7

inhibits inhibitory transmitter

Question 8

botulism toxin

Answer 8

inhibits acetylcholine release

Question 9

Heat labile enterotoxin (LT) produced by:

Answer 9

E coli

Question 10

What do superantigens do?

Answer 10

non specific cross bridge of Class II MHC molecules

Question 11

heat stable enterotoxins act on:

Answer 11

guanylyl cyclase, cGMP, cGMP kinase II

Question 12

2 common types of endotoxins

Answer 12

peptidoglycan and LPS

Question 13

type of secretion systems used by injected toxins

Answer 13

type III and type VI

Question 14

enterotoxins produced by enterotoxigenic e coli

Answer 14

LT and ST

Question 15

adhesin of enteropathogenic e coli

Answer 15

intimin

Question 16

enteroinvasive e coli produces syndrome identical to…

Answer 16

shigellosis

Question 17

salmonella adhere to…

Answer 17

apical surfaces of enterocytes

Question 18

autoinducers used by gram - bacteria in quorum sensing

Answer 18

N acyl homoserine lactones (AHL)