Glycolysis enzymes Flashcards
Phosphorylase
Degradation of glycogen or starch to G-1-P
Phosphoglucomutase
Isomerization of G-1-P to G-6-P
Hexokinase
- Phosphorylation of glucose to G-6-P
2. With ATP, phosphorylation of fructose to F-6-P
Phosphoglucoisomerase
Isomerization of G-6-P to F-6-P
Phosphofructokinase
Phosphorylation of F-6-P to FBP w ATP
Fructose bisphosphate aldolase
Cleaves FBP to GA-3-P and dihydroxyacetone phosphate
Triose phosphate isomerase
Inter converts GA-3-P and dihydroxyacetone-P
Glyceraldehyde-3- phosphate dehydrogenase
Oxidizes GA-3-P to 1,3-diphosphoglycerate using NAD+ and Pi, to form, NADP and H+
Phosphoglycerokinase
Generates ATP from ADP
Phosphoglyceromutase
Uses 2,3-diphosphoglycerate to convert 3-phosphoglycerate to 2-phosphoglycerate
Enolase
Enolization of 2-phosphoglycerate forms high E phosphate bond in phosphoenolpyruvate
Pyruvate kinase
Generates ATP from ADP
Lactate dehydrogenase
Reduces pyruvate to lactate using NADP AND H+