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Z_Pharma > Hormones > Flashcards

Hormones Flashcards

1
Q

MOA Leuprolide

A

GnRH analog

Increases LH and FSH secretion

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2
Q

MOA Ganirelix

A

GnRH antagonist

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3
Q

Rx
Endometriosis
Myoma Uteri

A

Leuprolide

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4
Q

MOA Pergolide

A

Like Bromocriptine

Dopamine 2 agonist

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5
Q

FSH analog

A

Follitropin Alfa

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6
Q

LH analog

A

Chroriogonadotropin Alfa

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7
Q

Used to increase F VIII in vWF

A

Desmopressin

also in central diabetes insipidus

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8
Q

MOA Desmopressin

A

Vasopressin V2 receptor agonist

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9
Q

MOA Conivaptan

A

Antagonist at V12, Va

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10
Q

Can cause drug induced hyperthyroidism

A

Clofibrate
Amiodarone
Methadone

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11
Q

Treatment amiodarone induced thyroid disease

A

thioamides,

or corticosteroids

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12
Q

Androgen (anabolic steroid) illegal performance drugs in athletes

A

Oxandrolone

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13
Q

Used in prostate cancer, androgen antagonist (competitive antagonist)

A

Flutamide

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14
Q

Used in surgical castration for prostate cancer

A

Nilutamide

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15
Q

Inhibits 5a reductase enzyme that converts testosterone to DHT

A

Finasteride

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16
Q

Glucocorticoid receptor used in medical abortion

A

Mifepristone
RU-486
Cytotec
(one and the same)

17
Q

GnRH antagonist used for controlled ovarian hyperstimulation (prevents premature LH surge)

A

Ganirelix

18
Q

GnRH analog

A

Leuprolide

19
Q

MOA Exemestane

A

Like Anastrozole
Letrozole
Inhibits aromatase reducing synthesis

20
Q

MOA Pioglitazone

A

Binds to PPAR gamma

regulates gene expression

21
Q

GLP-1 agonist

A

Exenatide

22
Q

Amylin Analog

A

Pramlintide

23
Q

GH spike near a.m.
3 am glucose- normal
6 am glucos- high

A

Dawn phenomenon

24
Q

evening dose of insulin is high
3 am glucose- low
6 am glucose- high

A

Somogyi effect

25
Q

evening dose of intermediate insulin inadequate
3 am glucose- high
6 am glucose- high

A

waning of insulin

26
Q

Antiobesity drug binds cannabinoid receptors

A

Rimonabant

27
Q

Antiobesity drug

Inhibits NE and serotonin reuptake

A

Sibutramine

28
Q

AE Alendronate

A

Osteonecrosis of the jaw

Esophagitis

29
Q

Bactericidal antibiotics

A 
Very Finely Proficient At Murder
Vancomycin
Fluroquinolones
Penicillin
Aminogly
Metro
30
Q

Used in secondary hyperparathyroidism in CKD

A

Calcitriol

Z_Pharma (11 decks)

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