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Z_Pharma > Antipsychotics Antiparkinsons > Flashcards

Antipsychotics Antiparkinsons Flashcards

1
Q

Antiparkinsons used in deterioration of drug effect in between doses

A

Entecapone

this is the “wearing off phenomenon”

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2
Q

Antiparkinsons used in alternating periods of improved mobility and akinesia during treatment

A

Apomorphine

“on-off phenomenon”

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3
Q

AE us erythromelalgia

A

Bromocripte

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4
Q

Antiparkinsons AE Gambling, hypersexuality

A

Pramipexole

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5
Q

Trimethobenzamine premedicate when taking ____ to prevent nausea

A

Apomorphine

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6
Q

Selegiline + ________ can cause fatal reaction

A

meperidine

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7
Q

Selegiline + ____________can cause serotonin syndrome

A

SSRIs

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8
Q

Antiparkinsons MAO Type B inhibitor

A

Selegiline

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9
Q

Antiparkinsons COMT inhibitor

A

Entecapone

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10
Q

Antiparkinsons Anticholinergic

A

Benztropine

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11
Q

Rx rabbit syndrome

A

Benztropine

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12
Q

Action Aripiprazole

A

D2 partial agonist

5HT 1A receptor

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13
Q

Dopamine hypothesis of Psychosis

A

Hyperactivity of dopaminergic systems

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14
Q

Antipsychotic causes agranulocytosis

A

Clozapine

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15
Q

Major metabolite of thioridazine, very poten

A

mesoridazine

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16
Q

Typical antipsychotics

A

Chlorpromazie
Thioridazine
Trifluoperazine
Haloperidol

17
Q

Monoamine hypothesis of depression

A

serotonin
NE
dopamine

18
Q

Contraindications antipsychotics

A

Depressed sensorium
Parkinsonism
Pregnancy
Respiratory depression

19
Q

Lowers lithium levels

A

Acetazolamide
Theophyline
Amniophylline

20
Q

Dose dependent AEs of phenytoin

A

20-30 Nystagmus, Ataxia
30-40 Mental changes, lethargy, dysarthria
40 Stupor

21
Q

Antiseizure, initially as antifolate

A

lamotrigine

22
Q

MOA Phenobarbital

A

Blocks Na and Ca

23
Q

AE is megaloblastic anemia, osteomalacia

A

Phenobarbital

24
Q

MC AE of ethosuximide

A

gastric distress

25
Q

First line drug in mild PD to delay introduction of levodopa

A

MAO B inhibitors:

Selegiline, Entecapone, Tolcapone

26
Q

First line therapy for PD

A

DRAgonists

Bromocriptine (D2), Pramipexole (D3)

27
Q

Alzheimers drug

Noncompetitive NMDA receptor antagonist

A

Memantine

Z_Pharma (11 decks)

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