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Z_Pharma > Heart > Flashcards

Heart Flashcards

1
Q

Acts as false neurotransmitter

A

Guanadrel

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2
Q

MOA alpha blockers in control of BP

A

block post synaptic a1 receptors on smooth muscle

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3
Q

increases risk for Congestive Heart Failure in ALLHAT

A

DOXAZOCIN

“NHLBI advises these patients to find an alternative”

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4
Q

Cardioselective Beta blockers

A 
Acebutolol
Atenolol
Betaxolol
Bisoprolol
Metoprolol

(AABBM)

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5
Q

Vasodilatory Beta blockers

A

Labetolol
Pindolol
Carvedilol

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6
Q

MOA Hydralazine

A

relax smooth muscle through fall in intracellular Ca concentration

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7
Q

MOA Minoxil

A

K channel opener

also diazoxide

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8
Q

SE first generation DHP CCBs

A

reflex tachycardia
stimulation of CNS
(Nifedipine is prototype)

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9
Q

Explain

Hypertension with OCPs containing estrogen

A

Contains ANGIOTENSINOGEN

can induce HPN

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10
Q

Most ACEIs are excreted renally except

A

Ramipril
Imidapril
(Renal and Hepatic)

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11
Q

Angiotensin receptor expressed only during injury

A

AT II

I is always expressed

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12
Q

Treatment of class 1a induced arrhythmias

A

SODIUM LACTATE

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13
Q

Class 1A drugs

A

QUINIDINE
PROCAINAMIDE
DISOPYRAMIDE

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14
Q

electrolyte changes exacerbate Digoxin Toxicity

A

Hypokalemia
Hypomagnesemia
Hypercalcemia

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15
Q

Rx arrythmia due to Digoxin Toxicity

A

LIDOCAINE

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16
Q

Phosphodiesterase inhibitors used in HF

A

MILRINONE

AMRINONE

17
Q

MOA Amiloride

A

Inhibit Epithelial sodium channels in the cortical collecting duct
also potassium sparers
also Triamterene

18
Q

Cause Gynecomastia

A 
Spirinolactone
Digoxin
Cimetidine
Alcohol
Ketoconazole

Some Drugs Create Awesome Knockers

19
Q

Site of Action ADH

A

Reabsorption of water under the control of ADH

20
Q

ADH antagonists apart from the Vaptans

A

DEMECLOCYCLINE

LITHIUM

21
Q

Thiazide diuretics

effect

A 
HyperGLUC
Hyperglycemia
HyperLipidemia
HyperUricemia
HyperCalcemia
22
Q

Inhibits NPC1L1 transporter, decreasing cholesterol absorption in intestine

A

EXETIMIBE

23
Q

Cholesterol analog, sterol absorption blocker

A

SITOSTEROL

24
Q

Pregnancy category of simvastatin

A

Category X

25
Q

Used in CAD for stabilization of atherosclerotic plaque

A

STATIN

26
Q

DOC to decrease Triglycerides

A

FIBRATES

Gemfibrozil
Bezafibrate
Fenofibrate

Z_Pharma (11 decks)

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