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Z_Pharma > Antibiotics > Flashcards

Antibiotics Flashcards

1
Q

Very narrow spectrum penicillin

Resistant to beta lactamase

A

Nafcillin
Oxacillin
Cloxacillin

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2
Q

Extended spectrum penicillin

A

Amoxicillin

Ampicillin

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3
Q

Antimicrobial coverage of extended spectrum penicillin

A

Amoxicillin HELPS kill Enterococci

Hemophilus
E Coli
Listeria
Proteus
Salmonella
Enterococci
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4
Q

Synergistic with aminoglycosides against pseudomonas

A

Piperacillin

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5
Q

First gen cephalosporins are not active to

A

Enterococcus
Listeria
MRSA
Chlamydia Clostridium

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6
Q

Narrowest spectrum among aminoglycosides

A

Amikacin

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7
Q

Binds to 50s to inhibit translocation

A

erythromycin

clindamycin

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8
Q

The most vsetibulotoxic and nephrotoxic aminoglycosides

A

gentamicin

tobramycin

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9
Q

Most ototoxic antibiotic

A

Kanamycin

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10
Q

Nephrotoxic effect of Aminoglycosides

A

Acute tubular necrosis

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11
Q

short acting sulfonamide

A

sulfisoxazole

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12
Q

intermediate acting sulfonamide

A

sulfamethoxazole

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13
Q

long acting sulfonamide

A

sulfadoxine

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14
Q

selective inhibitors of bacterial dihydrofolate reductase

A

trimethoprim

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15
Q

competitive inhibitors of dihydropteroate synthase

A

sulfonamides

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16
Q

SE of silver sulfadiazine which is used in burn patients

A

Acute hemolysis in G6PD deficiency

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17
Q

Tendinitis and tendon rupture

A

ciprofloxacin

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18
Q

1st gen fluoroquinolones

A

nalidixic acid

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19
Q

2nd gen fluoroquinolones

A

ciprofloxacin, norfloxacin

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20
Q

3rd gen fluoroquinolones

A

levofloxacin
sparfloxacin
grepafloxacin

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21
Q

4th gen fluoroquinolone

A

moxifloxacin

22
Q

Why was grepafloxacin withdrawn

A

cardiotoxicity

23
Q

Bactericidal

A

Very Finely Proficient At Murder

Vancomycin
Fluoroquinolones
Penicillin
Aminoglycosides
Metronidazole
24
Q

Nitrofurantoin can be used for UTI except

A

Proteus

Pseudomonas

25
Q

MOA metronidazole

A

reactive reduction by ferredoxin forming free radicals

26
Q

Anti TB drug AE

Drug induced lupus

A

izoniazid

27
Q

Antifungal inhibits microtubule formation

A

Griseofulvin

28
Q

Antifungal inhibits squalene oxidase

A

Terbinafine

29
Q

Antifungal inhibits glucan synthase

A

capsofungin

30
Q

Drugs for influenza

A

A- Amantadine/ Rimantadine

A and B-Oseltamivir

31
Q

Rx Hep B

A

IFN

Lamivudine

32
Q

Rx Hep C

A

IFN

Ribavirin

33
Q

Rx RSV infection

A

Ribavirin

34
Q

DOC Malaria in pregnant patient

A

Quinine

35
Q

SE of quinine

A

Cinchonism
(Headache, tinnitus, vertigo)
Hemolysis in G6PD deficient

36
Q

Chemoprophylaxis multidrug resistant malaria

A

Doxycycline

(S)- chloroquine 500 mg/tab 1 tab weekly
chloroquine (R)- mefloquine 250 tab 1 tab weekly

37
Q

DOC for uncomplicated malaria in the philippines

A

Artemether lumefantrine

38
Q

Areas of high malarial endemicity

A

Palawan
Ifugao
Kalinga Apayao
Agusan Del Sur

39
Q

Areas of multidrug resistance

A

Palawan
Davao Del Norte
Compostela Valley

40
Q

DOC african sleeping sickness

A

MELARSOPROL

41
Q

DOC Advanced african sleeping sickness

A

EFLORNITHINE

42
Q

DOC Chagas Disease

A

Nifurtimox

43
Q

DOC Leishmaniasis

A

Sodium sibogluconate

44
Q

DOC Toxoplasmosis

A

Pyrimethamine- Sulfadiazine

45
Q

DOC Whipworm

A

Mebendazole

46
Q

DOC flilaria

A

DEC

47
Q

May cause mazotti in onchocerca

A

DEC

48
Q

DEC Hookworm and roundworm

A

Pyrantel Palmoate

49
Q

DOC Trichinosis

A

Thiabendazole

50
Q

DOC Trematodes

Schistosoma, Paragonimus, Clonorchis…

A

Praziquantel

Z_Pharma (11 decks)

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