Hormones Flashcards
Where does the anterior pituitary arise from in development?
Rathke’s pouch
What type of gland is the anterior pituitary?
Endocrine
What type of tissue is the posterior pituitary?
Nervous tissue
How is GnRH secreted?
In a pulsatile fashion
What does testosterone do to the HPA?
negative feedback
What does oestrogen at intermediate concentrations do to HPA?
negative feedback
What does progesterone do to HPA?
negative feedback
What does oestrogen at high concentrations do to HPA?
stimulates it for a LH surge
What does the hypothalamus secrete?
GnRH
What does the anterior pituitary secrete?
LH and FSH
What does LH do?
Stimulates Leydig cells to release testosterone
Stimulates Theca cells to secrete oestrogen (androgens then converted to oestrogen by granulosa cells)
What does FSH do?
Stimulates granulosa cells to develop graafian follicles and ovulation by oestrogen
Stimulates Sertoli cells to produce spermatogenesis
What stimulates ovulation?
LH surge
What is LH’s role after ovulation?
stimulates corpus luteum to secrete progesterone and oestrogen
What does prolactin do?
Inhibits ovulation