Hormones Flashcards

1
Q

Where does the anterior pituitary arise from in development?

A

Rathke’s pouch

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What type of gland is the anterior pituitary?

A

Endocrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What type of tissue is the posterior pituitary?

A

Nervous tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How is GnRH secreted?

A

In a pulsatile fashion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What does testosterone do to the HPA?

A

negative feedback

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What does oestrogen at intermediate concentrations do to HPA?

A

negative feedback

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What does progesterone do to HPA?

A

negative feedback

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What does oestrogen at high concentrations do to HPA?

A

stimulates it for a LH surge

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What does the hypothalamus secrete?

A

GnRH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What does the anterior pituitary secrete?

A

LH and FSH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What does LH do?

A

Stimulates Leydig cells to release testosterone

Stimulates Theca cells to secrete oestrogen (androgens then converted to oestrogen by granulosa cells)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What does FSH do?

A

Stimulates granulosa cells to develop graafian follicles and ovulation by oestrogen
Stimulates Sertoli cells to produce spermatogenesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What stimulates ovulation?

A

LH surge

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is LH’s role after ovulation?

A

stimulates corpus luteum to secrete progesterone and oestrogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What does prolactin do?

A

Inhibits ovulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the actions of testosterone?

A

Behaviour - sex and aggression
Maintenance of male internal genitalia
Metabolic effects

17
Q

Why is there a waiting phase?

A

Because conceptus is too small to signal is presence so body assumes it’s pregnant until it knows 14 days later

18
Q

What are oestrogens effects in the follicular phase?

A
Muscular contractions in the fallopian tube 
Stimulate growth and motility 
Thickened endometrium 
Thin, cervical mucous
Depress appetite 
Calcium metabolism
19
Q

What are oestrogens effects in the luteal phase ?

A
reduced fallopian tube motility 
further thickening of myometrium 
thick, acidic mucous 
catabolic change 
basal body temp 
mammary tissue changes
20
Q

What triggers apoptosis of corpus luteum?

A

fall in oestrogen and progesterone
endometrium collapses
apoptotic cell death
shred as a menstrual bleed, spiral arteries contract to reduce bleeding

21
Q

Why is oestrogen, progesterone and inhibin low in follicular phase?

A

no theca

22
Q

What controls the reproductive cycle?

A

Pelvic clock