Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Hormones > Flashcards

Hormones Flashcards

1
Q

DOC obesity

A

Liraglutide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

CHF is a complication of which DPP4 inhibitor

A

Saxagliptin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Risk of hepatitis is increased with which DPP4 inhibitor

A

Vildagliptin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Only gliptin that is excreted through liver and not kidney

A

Linagliptin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Name the amylin analogue

A

Pramlintide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which drugs can be used in both type one and type two diabetes mellitus?

A

Pramlintide and insulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Only insulin which is milky cloudy white

A

Isophane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Insulin which has acid pH

A

Glargine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Insulin which forms white crystals with other insulin in same syringe

A

Glargine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Longest acting insulin

A

Degludec

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

The only insulin for which rate of absorption does not depend on the site of injection is

A

Glargine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Most common site for injection of insulin

A

Abdomen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Drug of choice for diabetic ketoacidosis and route

A

IV regular insulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Sulfonylurea of choice in elder

A

Glipizide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Pioglitazone decreased insulin resistance by acting on which tissue?

A

By acting on adipose tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Side effects of metformin

A

B12 deficiency due to decreased calcium dependent b 12 absorption

LACTIC ACIDOSIS

17
Q

C/I of Metformin

A

CHF
Severe lung disease
Renal failure
Hepatic failure
Chronic alcoholics

18
Q

Drugs causing weight loss

A

GLP1 agonists
Metformin
SGLT2 #
Amylin analogues

19
Q

Which classes of anti diabetic drugs reduce CVS mortality?

A

GLP1 agonists and SGLT2 #

20
Q

GLP2 agonists name

A

Teduglutide

21
Q

Most potent steroids

A

Dexamethasone and betamethasone

22
Q

Least potent steroid

A

Hydrocortisone

23
Q

Longest acting glucocorticoids

A

Dexamethasone and betamethasone

24
Q

Shortest acting steroid

A

Hydrocortisone

25
Q

Most potent topical steroid

A

Clobetasol propionate ointment

26
Q

Steroids are used in pregnancy for

A

Surfactant maturation

27
Q

Mechanism of anti-inflammatory and immuno suppressive action of steroids

A

Decrease the production of inflammatory mediators like I L1 , IL6and TNF alpha
Increase production of anti-inflammatory mediators like I 10 and annexin1
Lymphocyte apoptosis as well as cause re-distribution of lymphocytes

28
Q

Only drug to decrease mortality in Covid

A

Steroids

29
Q

Infections in which steroids can be used

A

H. Influenza, meningitis, Covid pneumonia.

30
Q

Which drug inhibits bone resorption and stimulates bone formation at the same time?

A

Strontium ranelate

31
Q

Drugs that stimulate bone formation

A

Teriparatide, abolaparatide, romosozumab

32
Q

Most potent bisphosphonate

A

Zoledronate

33
Q

Mechanism of action of second and third generation bisphosphonates

A

Block Farnesyl pyrophosphate synthase which is required in mevalonate pathway, leading to apoptosis of osteoclasts

34
Q

Mechanism of action of first generation base phosphonates

A

Abnormal ATP production which cannot be used by osteoclasts leading to the apoptosis

35
Q

What is the advice given to patients on bisphosphonates ?

A

To prevent esophagitis, patient is advised to take the drug with a full glass of water and not lie down for 30 minutes
The same advice is given for patients taking tetracycline

36
Q

Anti sclerostin antibody name

A

Romosozumab

37
Q

Fastest acting, anti thyroid drugs

A

Iodide

Pharmacology (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions