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Pharmacology > Antiviral And Antiretroviral Drugs > Flashcards

Antiviral And Antiretroviral Drugs Flashcards

1
Q

Name NRTIs

A

Zidovudine
Lamivudine
Stavudine
Emtricitabine
Tenofovir
Abacavir
Didanosine

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2
Q

Name NNRTIs

A

Nevirapine
Efavirenz
Etravirine
Delavirdine
Doravirine
Rilpivirine
(NEED Rti)

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3
Q

DOC in prevention of perinatal transmission of HIV

A

Nevirapine

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4
Q

NNRTI that can be used w Rifampicin

A

Efavirenz

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5
Q

Regimen for HIV treatment and Post exposure prophylaxis

A

Tenofovir + Lamivudine + Dolutegravir / 2 Lopinavir/Ritonavir / 3 Efavirenz

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6
Q

Side effects of NRTI

A

Lactic acidosis, peripheral neuropathy, myopathy and pancreatitis
(Due to mitochondrial toxicity)

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7
Q

SJS is a side effect of which antiretroviral

A

Nevirapine

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8
Q

Only NRTI ineffective in HIV2 is

A

Abacavir

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9
Q

Which Protease inhibitor is used as a boost and why?

A

Ritonavir - strong microsomal inhibitory action , can competitively inhibit metabolism of other PIs

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10
Q

Cobicistat is used w which drugs?

A

Atazanavir, Darunavir, Elvitegravir

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11
Q

Protease inhibitors

A

Ritonavir
Atazanavir
Indinavir
Nelfinavir
Saquinavir
Fosamprenavir
Lopinavir
Darunavir

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12
Q

Classes under antiretrovirals

A

NRTIS
NNRTIS
Integrase inhibitor
Protease inhibitors
CCR5 receptor inhibitors
Entry inhibitors

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13
Q

HSV keratitis topical drug?

A

Idoxuridine

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14
Q

DOC resistant herpes?

A

Foscarnet

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15
Q

Doc CMV retinitis

A

Oral valaganciclovir

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16
Q

Drugs not to be used with ganciclovir

A

Zidovudine, linezolid, anticancer drugs (Bone marrow suppression)

17
Q

Doc recurrent laryngeal papillomatosis

A

Cidofovir i/v

18
Q

Drug with multiple effects on electrolyte balance

A

Foscarnet

19
Q

Drugs that prevent viral attachment & entry

A

Enfuvirtide, maraviroc, docosanol, palivizumab

20
Q

Anti influenza drug used in Parkinsonism

A

Amantidine

21
Q

Neuraminidase inhibitors

A

Oseltamivir, zanamivir

Pharmacology (8 decks)

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