Hormone Measurement Flashcards
High TSH and low thyroxine indicates what?
Hypothyroidism due to thyroid dysfunction
How do you test adrenal cortex underactivity?
Stimulate gland with synthetic ACTH
What type of antibody is preferred for immunoassays?
Monoclonal
What is the most used technique for determining hormone cencentrations?
Immunoassays
What are heterophilic antibodies?
Antibodies possessed by the patient that are reactive against mouse antibodies
What do you use the dexamethasone suppression test for?
Test cortisol production by the adrenal cortex
Low TSH and low thyroxine indicates what?
Hypothyroidism due to pituitary dysfunction
What are some stimulus for the GH stimulation test?
Exercise, hypoglycaemia (dangerous), arginine
Why is measuring TSH better than measure thyroxine for testing the thyroid gland?
Because TSH rises before thyroxine falls
The gold standard test for diabetes is what?
The glucose tolerance test
Why use dynamic tests?
To look for subclinical disease
Investigating abnormal results
High serum cortisol post dexamethasone indicates what?
Failure of suppression > Evidence of Cushing’s syndrome
What are dynamic tests?
Sampling at multiple time points
May involve stimulating or suppressing gland
