Hormonal Communication Flashcards

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1
Q

endocrine system

A

a communication system using hormones as signalling molecules

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2
Q

hormones

A

proteins or steroid molecules that are released by endocrine glands into blood and they act as messengers carrying the signal to the specific target organ/tissue

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3
Q

target cells

A

for non-steroid hormones cells that posses a specific receptor on their membrane- shape is complementary to the hormone

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4
Q

adrenal cortex

A

outer layer of the adrenal gland

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5
Q

adrenal gland

A

one of a pair of glands lying above the kidneys which release adrenaline and other hormones (corticoids)

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6
Q

adrenaline

A

hormone which stimulates the body to prepare for fight or flight

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7
Q

adrenal medulla

A

inner layer of the adrenal gland

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8
Q

beta cells

A

found in the islets of Langerhans that secrete insulin

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9
Q

glucagon

A

hormone that causes an increase in blood glucose concentration

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10
Q

insulin

A

hormone released from the pancreas that causes blood glucose levels to go down

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11
Q

diabetes mellitus

A

condition which blood glucose levels can’t be controlled effectively

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12
Q

stem cells

A

unspecialised cells that have the potential to develop into any type of cell

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13
Q

types of hormones

A

protein and peptide hormones (derivatives of amino acids)- not soluble
steroid hormones- soluble so enter nucleus and have direct effect

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14
Q

endocrine glands

A

ductless glands that consist of a group of cells that manufacture and release a hormone directly via capillaries into the blood

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15
Q

endocrine organs

A

pituitary gland, thryoid gland, thymus, adrenal glands, pancreas, ovaries, testes

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16
Q

how do target cells work

A

for non-steroid hormones, must possess a specific receptor complementary to the shape of the hormone to initiate changes in the cell
each hormone is different so only the target cells with specific receptor will respond

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17
Q

how are target cells distributed

A

when receiving an endocrine signal, either grouped together in a target tissue or widely dispersed in a number of tissues

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18
Q

first messenger

A

non-steroid hormones, signalling molecules outside the cell that bind to the membrane and initiate an effect inside the cell

19
Q

second messenger

A

first causes the release of another signalling molecule in the cell, stimulating a change in the activity of the cell

20
Q

roles of the pancreas

A

digestion- secretes digestive enzymes

metabolism- regulation of carbs, lipids etc., produces primary messengers

21
Q

2 main secretions of the pancreas

A

pancreatic juices containing enzymes secreted into the s. intestine
hormones secreted from islets of Langerhans into the blood

22
Q

what enzymes does fluid from the pancreatic duct contain

A

pancreatic amylase, trypsinogen, lipase, sodium hydrogencarbonate to make it more alkaline

23
Q

endocrine tissues

A

islets of Langerhans contains alpha and beta cells

24
Q

alpha cells

A

secrete glucagon to raise glucose concentration

25
Q

beta cells

A

secrete insulin to lower glucose concentration

26
Q

glycogenesis

A

glucose converted to glycogen

27
Q

glycogenolysis

A

glycogen converted to glucose

28
Q

gluconeogenesis

A

breaking down of triglycerides and proteins

29
Q

glycosuria

A

glucose in the urine

30
Q

glucose levels must be constant (4-6mmol dm3) because

A

respiration is a continuous process in all living cells

high concentration of glucose affects the water potential of the blood plasma

31
Q

hypoglycaemia

A

inadequate delivery of glucose to tissues and brain causing tiredness, irritability, even seizures, unconsciousness, death

32
Q

hyperglycaemia

A

glucose concentration rises too high for long periods causing organ damage, osmotic water loss, damages blood vessels

33
Q

how do hormones act on hepatocytes

A

when there is excess glucose, it is converted to glycogen and when glucose is needed it is converted back

34
Q

hepatocytes

A

liver cells that can store glycogen

35
Q

if blood glucose concentration rises too high

A

it is detected by beta cells, secrete insulin into the blood, travels through the body to target cells

36
Q

insulin

A

a small protein and hormone of 51 a.a.

37
Q

how do liver cells release glucose from glycogen

A

have a specific membrane receptor, insulin binds and causes glucose channels to merge with the membrane

38
Q

if blood glucose concentration drops too low

A

detected by alpha cells, secrete glucagon into the blood to act on target cells

39
Q

why is glucose concentration controlled by negative feedback

A

insulin and glucagon are antagonistic but fluctuate around the required concentration

40
Q

glucagon

A

a small protein hormone containing 29 a.a.

41
Q

diabetes mellitus

A

a condition in which the body is no longer able to produce sufficient insulin to control its blood glucose concentration

42
Q

other names for type 1 diabetes

A

insulin-dependent or juvenile-onset diabetes because it starts in childhood

43
Q

other names for type 2 diabetes

A

non-insulin-dependent diabetes