homeostasis Flashcards

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1
Q

what secrete the alpha and beta cells?
and which hormones do each cell secrete?
🌄🌕🌙💞

A

islets of langerhan
alpha- glucagon
beta- insulin

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2
Q

what if blood glucose levels are too high?
🤍

A

insulin is secreted from beta cells
triggers liver and muscle cells to take up glucose (& store as glycogen)
inverts glucose to glycogen (glycogenesis)
cells respire more glucose

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3
Q

define homeostasis🌃

A

the regulation of a cell or organism to maintain stable optimum conditions in response to internal and external changes

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4
Q

define hormone🌞

A

chemical messages secreted by the glands of the endocrine system- they’re released directly into the blood stream by endocrine glands and travel to cells in the blood- they have a specific comp receptor- these are the target cells

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5
Q

endocrine systems def🌺

A

this uses hormones which are released form specialised tissues called glands and travel through the blood stream to various effector organs

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6
Q

why is glucose constantly needed in cells?🧚🏼‍♀️

A

to produce ATP and provide energy. also contributes to the water potential of blood outside the cells

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7
Q

what’s ultrafiltration?🧜🏼‍♀️

A

the wider lumen of the afferent than efferent arteriole causes high hydrostatic pressure which forces small molecules out of blood plasma into the bowman’s capsule. capillary walls + filtration slits stop large molecules entering filtrate

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8
Q

what’s selective re absorption?🧞‍♀️

A

as the glomerular filtrate moves through the PCT, 85% of it is reabsorbed into the blood, including: all the glucose and AA, most the water, some ions.
cells lining the PCT are adapted to maximise absorption

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9
Q

describe part 1 of the reabsorption of water👑

A

loop of henle creates a low water pot in the medulla. na+ are AT out the ascending limb to the descending limb which incs the conc of na+ in medulla- lowering the water pot in the tissue around the loop. water follows this down the osmotic gradient and is reabsorbed into the blood. filtrate passes into the DCT where even more water is reabsorbed to blood by osmosis.

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10
Q

describe part 2 of the reabsorption of water in the blood🌙

A

concentration of urine enters the collecting duct. the permeability of the memb of this part of the nephron is regulated by ADH in blood. osmoreceptors in the hypothalamus control the release of ADH from the pituitary gland in the brain and its controls how much enters the urine.

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11
Q

where does ultrafiltration occur?🌑
which arteritole enters and leaves the glomerulus?🌑
what is the glomerulus?🌑

A

glomerulues
afferent enters
efferent leaves
bundle of capillaries

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12
Q

which arteriole has a wider lumen?🏰

A

afferent

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13
Q

role of the renal artery?🤍
role of the renal vein?🤍

A

artery-supplies the kidney with blood from the heart via the aorta
vein-returns blood to the heart via the vena cava

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14
Q

why does the urine not contain:
protein and blood cells?
glucose?
💍

A

p+bc: proteins are too large to be filtered out the blood
g: all glucose is absorbed at the selective reabsorption stage in the PCT

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15
Q

selective reabsorption adaptations?🦜

A

microvilli provide a large SA for reabsorption
lots of mitochondria provide energy for AT

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16
Q

how does the length of the loop of henle differ for a desert animal compared to human?🎀

A

they have longer loop of henle
so more na+ out- resulting in more water being reabsorbed into the blood and very concentrated urine

17
Q

selective reabsorption of glucose please😔🌺

A

glucose absorption (co transport ya)
conc of na+ in PCT is decreased as na+ are AT out PCT into the blood
due to conc gradient na+ diffuse down into the cells lining the PCT- bringing gluc w it (co transport)
glucose then diffuses from PCT epithelial cell into the blood.
this is how all the gluc is reabsorbed

18
Q

… in the … controls the release of ADH from the … in the brain and it controls how much water enters the urine😵‍💫

A

osmoreceptors
hypothalamus
pituitary gland

19
Q

what’s the 2nd messenger model?🪸

A

when hormone isn’t lipid-soluble so can’t diffuse thru bilayer
glucagon bind to receptor - activates internal G-protein
adenyl cyclase catalyses ATP - cAMP
sets off a cascade of chemical reactions which activate kinase enzyme to convert glycogen to glucose (glycogenolysis)

20
Q

what does adrenaline catalyse and inhibit?🌺

A

catalases glycogenolysis
inhibits glycogenesis

21
Q

what does insulin do to regulate blood glucose🍹

A

attaches to receptors on target cells
regulates the inclusion of channel proteins in the surface membranes of target cells
activates glycogenesis

22
Q

what does glucagon do to regulate blood glucose?🐉

A

attaches to receptors in target cells
activates glycogenolysis
activates glyconeogenesis