HMG-COA reductase inhibitors "statins"

Question 1

names

Answer 1

-atorvastatin (lipitor)
-fluvastatin (lescol)
-lovastatin (altoprev)
-pitavastatin (livalo)
-simvastatin (zocor)
-rosuvastatin (crestor)

Question 2

uses

Answer 2

-hyperlipidemia
-CAD primary prevention and secondary

Question 3

actions

Answer 3

-inhibits enzyme HMG-CoA reductase

Question 4

side effects

Answer 4

-headache
-nausea
-dizziness
-constipation
-cramping
-abdominal pain
-hyperglycemia

Question 5

nursing considerations

Answer 5

-monitor liver enzymes (ALT/AST)
-monitor therapeutic response to lower LDL and increase HDL
-avoid grapefruit
-do not give if pregnant or breastfeeding
-monitor for rhabdomylosis
*muscles are damaged
*dark urine
*muscle pain, tenderness, weakness
*malaise or fever