bronchodilator Methylxanthines and xanthine derivatives

Question 1

names

Answer 1

-aminophylline
-dyphylline (lufyllin)
-oxtriphylline (choledyl SA)
-theophylline (theochron)

Question 2

action

Answer 2

-dilates bronchi
-stimulate CNS for bronchodilation
-relaxation of smooth muscle in bronchi

Question 3

uses

Answer 3

-relief and prevention of bronchial asthma
-tx of bronchospasms seen in COPD

Question 4

side effects

Answer 4

-tachycardia
-palpitations
-ECG changes
-nervousness and anxiety
-irritable

Question 5

theophylline level

Answer 5

therapeutic: 10-20

signs of toxicity:
- tonic clonic seizures
-tachycardia and dysrythmias