Antithyroid

Question 1

Names

Answer 1

-methimazole (tapazole)
-propylthiouracil (PTU): Prevent Thyroid from being Up

Question 2

Action

Answer 2

-inhibits manufacture of thyroid hormone
-does not affect existing thyroid hormones circulating in the blood or stored in the thyroid gland

Question 3

Side Effects

Answer 3

-hay fever
-rash
-headache
-N/V
-paresthesias

Question 4

Adverse Reactions

Answer 4

-agranulocytosis = increased risk of infection
-drug induced hepatitis: monitor liver values

Question 5

Uses

Answer 5

-hyperthyroidism
-thyrotoxicosis
-graves disease (autoimmune disease that causes hyperthyroidism)
-used before thyroidectomy

Question 6

Patient Education

Answer 6

-may take 1-2 weeks to see full effect
-report signs of hypothyroidism (bradycardia, weight gain, lethargy, cold intolerance, depression)
-report s&s of infection to HCP
-do not stop!! could cause thyroid storm

Question 7

Pregnancy Considerations

Answer 7

• use with caution during pregnancy bc it can cause hypothyroidism in fetus
• if necessary, propylthiouracil is preferred (does not cross placenta)