HIV

Question 1

PEP protocol for healthcare workers

Answer 1

Begin ASAP
2-3 Antiviral drugs for 1 month
Follow up lab tests 1, 3 and 6 months up to 1yr

Question 2

PEP HIV 3 drug regimen

Answer 2

Truvada (contains tenofovir and emtricitatbine)

plus Raltegravir or Dolutegravir

Question 3

Window Period

Answer 3

lack of HIV antibodies - highly infectious

Question 4

Viral set point

Answer 4

Balance between amount of HIV and the immune response

Question 5

Name a NRTI (nucleoside reverse transcriptase inhibitor) drug and their S/E

Answer 5

Zidovudine, Lemovudine
S/E: 
Lactic acidosis 
Hepatic Steatosis
Fat redisposition 
N/V, diarrhea 
pancreatitis

Question 6

Name a NNRTI (non-nucleoside reverse transcriptase inhibitor) drug and their S/E

Answer 6

Efavirenz
S/E:
Rash may cause Steven-Johnson Syndrome
Hepatotoxicity

Question 7

Name a PI (Protease inhibitor) drug and their S/E

Answer 7

Indinavir, Ritonavir 
S/E:
Dyslipidemia 
Hyperglycemia (insulin resistance)
Increased risk for bleeding

Question 8

Name a Integrase inhibitor drug

Answer 8

Raltegravir

Question 9

Name a Fusion inhibitor drug

Answer 9

Enfuvirtide