History/Groups/Units Flashcards

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1
Q

Watch Dial Painters

A

Exposed to ingestion of large amounts of radium due to drawing bristles of sable paint brushes between lips to “sharpen” point during the the 1920s and 30s primarily in Illinois and New Jersey. Incorporated into bone tissue causing decalcification of bone, sarcoma, and carcinoma

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2
Q

Navajo Miners

A

Exposed to ingestion of uranium dust due to mining in the 1950s and 60s. 50% dies of lung cancer. Mines in NM and AZ that employed over 15,000 minors, mainly navajo. Average dose was 10Sv (1000 rem). Contaminated homes/families with radioactive dust brought home on clothing.

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3
Q

Early Radiology Workers

A

High Exposure of radiation exposure to hands/face due to no protective equipment from 1896-1910’s, resulting in an increased incidence of aplastic anemia and leukemia.

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4
Q

Thorotrast Patients

A

Early contrast agent used in angiography containing 25% Thorium Dioxide (Alpha Emitter), uptake into the liver and spleen causing an increased incidence of liver cancer, cancer of the spleen, biliary carcinoma, and angiosarcoma.

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5
Q

Infant Thymus Glands

A

In an attempt to treat enlargement of the thymus gland, radiation treatments were used on infants in the 1940’s & 50s. Enlargement due to infections/respiratory distress in infants. Theraputic dose of 1.2-60 Gray (120-6000 rads).

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6
Q

Marshall Islanders

A

Fallout pattern of radiation in air in Bikini Atoll in 1954. An unexpected wind shift during a nuclear test carried the fallout pattern over the inhabited islands. The average dose to thyroid = 12 Gray (1200 rad)

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7
Q

Hiroshima and Nagasaki

A

Radiation exposure due to atomic bomb killing approximately 90,000 immediately and 70,000 injured. All survivors with various degrees of radiation exposure. Studied survivors found increased incidence of leukemia, thyroid and lung cancer and bone/breast cancer.

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8
Q

Chernobyl

A

In 1986 a meltdown/explosion at a nuclear power plant with no international notification, discovered by Swedish monitoring systems. Soviets tried to cover it up. VERY limited early assistance/evacuation efforts; delays in administering aid resulted in million of people developing radiation induced illnesses.

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9
Q

Fukushima Daiichi

A

Radioactive debris released due to an earthquake and tsunami. Earthquake struck causing shutdown of reactors, backup generators kicked on and were then flooded by tsunami causing a loss of power to run the cooling pumps leading to overheating of the reactor core with meltdown.

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10
Q

Exposure in Air

A

Measured by:
Roentgen (R - traditional)
or
SI Units - Air Kerma (Gya - Grays in Air)

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11
Q

Roentgens

A

Used to measure ionization in air as a result of an exposure to X-ray or gamma rays

1 R = 2.58 x 10(-4) coulombs per kilogram

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12
Q

Air Kerma, Grays in Air (Gya)

A

Measures the amount of energy absorbed in any medium

1Gy = 100 rads

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13
Q

Energy Absorbed

A

Dose to humans

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14
Q

Rads

A

Traditional units for measuring energy absorbed

RAD = Radiation Absorbed Dose

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15
Q

Gray in Tissue (Gyt)

A

SI unit for measuring energy absorbed

Gyt = Grays in Tissue

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16
Q

Dose Equivelent

A

Tissue damage due to dose

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17
Q

Rem

A

Traditional unit for measuring dose equivelent.

Different types of radiation produce different types of biological effects in living tissue.

Rem = RAD x QF (absorbed dose x quality factor)

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18
Q

Sievert

A

SI unit for measuring dose equivelent

19
Q

Activity

A

Amount of a radioactive material used commonly in radiation therapy of nuclear medicine.

20
Q

Curie

A

Traditional unit for measuring activity (Ci) or radionuclide decay.

21
Q

Becquerel

A

SI unit for measuring activity

22
Q

LD 50/60

A

The dose to kill 50% of a population within 60 days after exposure

23
Q

lethal dose is approximately

A

300-400 rads without medical intervention

24
Q

Doubling Dose

A

measures the effectiveness of radiation in causing mutations

25
Q

Male Sterility dose

A

the higher the dose, the greater the risk

26
Q

Temporary Male Sterility Dose

A

200 rads may cause temporary sterility for as long as 12 months

27
Q

Permanent Male Sterility Dose

A

500-600 rads may cause this

28
Q

Female Sterility Dose

A

The amount of dose determines the risk of sterility

29
Q

Temporary Female Sterility Dose

A

200 rads will usually result in temporary female sterility

30
Q

Permanent Female Sterility Dose

A

a single dose of 500 rads will cause permanent sterility

31
Q

Uranium Half Life

A

U238 has a half life of 4.5 billion years

32
Q

Uranium

A

A fuel for nuclear power and weapons

33
Q

Since the 1940s

A

radiation workers have no documented increase in adverse health effects due to their occupational exposure.

34
Q

Thymus gland

A

As a infant, this gland is basically fully sized (very large for an infant)

35
Q

1 out of 300

A

Survivors of Hiroshima/Nagasaki died of malignancy attributed to the whole body radiation exposure; a tribute to the human bodes ability to repair itself

36
Q

Radiologic Units

A

Used to quantify the amount of radiation healthcare workers and patients receive, used for dose, exposure, and air exposure.

37
Q

Traditional Units

A

In the USA we routinely use these whereas the rest (about) of the world uses SI units

38
Q

LD 50/30 vs 50/60

A

For humans, the LD 50/60 is typically used due to our slower recovery rate and inaccurate results if only 30 days are given to determine whether or not death will occur.

39
Q

Doubling Dose

A

Measures the radiation dose that causes the number of spontaneous mutations in a given generation to increase by 2 (double). Estimated to be a mean dose of 156 rem and was determined by the Japan bomb survivors

40
Q

Low Dose - Sterility

A

a dose as low as 10 rads can depress the sperm count, may also cause genetic mutations in further generations

41
Q

Sterility in females

A

Ovaries are very radiosensitive as a child/teen. From age 20-30 they are least radiosensitive. From age 30 on, their radiosensitvity increases constantly until menopause because the new ova being destroyed are not replenished.

42
Q

Sterility in Females - Small dose

A

Doses as small as 10 rads may cause menstrual irregularities and may cause genetic damage. Women should wait 30 days after a significant X-ray exposure before attempting to achieve conception.

43
Q

Dose Response Curve

A

.