Histoplasmosis

Question 1

What bacteria is associated with Histoplasmosis?

Answer 1

Histoplasma capsulatum

Question 2

Histoplasma capsulatum is associated with what?

Answer 2

with nitrogen rich soil as well as birds and bat droppings

Question 3

What does it mean that Histoplasma capsulatum are dimorphic ascomycetes?

Answer 3

They are fungi that exist in either yeast form or mold form (mycelial form)

Question 4

At what temperature is Histoplasma capsulatum in yeast form?

Answer 4

37 degrees C

Question 5

at what temperature does Histoplasms capsulatum grow in mold form?

Answer 5

20-25 degrees Celsius

Question 6

What are the two varieties of Histoplasmosis?

Answer 6

1) Histoplasma capsulatum variety capsulatum

2) Histo capsulatum variety duboisii

Question 7

Does Histoplsma capsulatum have spores?

Answer 7

yes?

Question 8

spores of Histoplasma capsulatum attack what?

Answer 8

macrophages

Question 9

Symptoms if 95% of the infected are what?

Answer 9

mild

Question 10

Infected macrophages with Histoplasma capsulatum do what?

Answer 10

carry spores through circulatory and lymphatic system

Question 11

Patience may develop _____ with symptoms similar to those of tuberculosis?

Answer 11

chronic pulmonary histoplasmosis

Question 12

patients may develop _____ characterized by ulcers?

Answer 12

chronic cutaneous histoplasmosis

Question 13

Immunocompromized patients may develop systemic histoplasmosis characterized by what?

Answer 13

enlargment of spleen and liver; death may result

Question 14

Ocular histoplamosis may develop. inflammed red eyes indicate what?

Answer 14

type I hypersensitivity to the fungus

Question 15

what is the treatment of histoplasmosis?

Answer 15

• Itraconazole
• ketoconazole
• Amphotericin B.

Question 16

The symptoms of Histomplasmosis are similar to what?

Answer 16

Those of pneumonia

Question 17

infection of histoplasmosis in some people is due to what?

Answer 17

Inhalation

Question 18

Histopplasma capsulatum variation duboisii is what?

Answer 18

lymphadenopathy with lesions on the skin and bones

Question 19

What are the symptoms of Histoplasmosis?

Answer 19

• Dry cough
• shortness in breath
• chest pain
• fever
• chills
• headache

Question 20

How is histoplasmosis transmitted?

Answer 20

airborne spores

Question 21

Where is histoplasmosis prevalent?

Answer 21

Eastern US states along with Ohio River Valley and south America