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Histopathology Flashcards

1
Q

Mobile rubbery breast lump

A

Fibroadenoma

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2
Q

Bloody discharge without a lump

A

ductal papilloma

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3
Q

calcification, discharge, lump

A

DCIS

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4
Q

incidental finding with no calcification or mass found and can recur and can be bilateral

A

LCIS

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5
Q

Loss of e-cadherin and single file chain cells

A

Lobular carcinoma

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6
Q

Rough nipple with discharge and retraction

A

Paget’s disease of the nipple

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7
Q

Leaf like fibroepithelial and stromal proliferation, artichoke like appearance

A

Phylloides tumour

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8
Q

Stellate pattern sclerosing lesion proliferating glandular tissue

A

Radial scar

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9
Q

Drug side effect breast enlargement

A

gynaecomastia

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10
Q

Thyroid cancers associated with RET mutation and raised calcitonin. linked to MEN 2B.

A

Medullary

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11
Q

Thyroid cancer with BRAF mutation and psammoma bodies. Most common

A

Papillary

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12
Q

Thyroid cancer with RAS mutation well differentiated but mets quite early

A

Follicular

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13
Q

Thyroid cancer that is poorly differentiated with TP53 mutation. Very aggressive and seen in older people and rare

A

Anaplastic

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14
Q

Type 1 endometrial cancer

A

Oestrogen related in younger women

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15
Q

Type 2 endometrial cancer

A

Older women with atrophic endometriosis, papillary clear cell cancer

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16
Q

Liver disease with copper affecting Basal ganglia

A

Wilson’s

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17
Q

Portal HTN, ANA antibody positive and liver disease

A

PBC

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18
Q

Aflatoxin and thorotrast exposure old man

A

Hepatocellular Carcinoma

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19
Q

What indicatres colectomy for a UC patient when you biopsy the polyp

A

Dysplastic Polyps

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20
Q

What would you see on Crohn’s histology

A

Transmural inflammation, non-caseating granulomas

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21
Q

Cancer marker for colon

A

CEA

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22
Q

Continuous colonic lesions

A

UC

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23
Q

IBD is associated with what liver condition

A

PSC

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24
Q

Thunder clap headache, ruptured berry aneurysm

A

sub-arachnoid haemorrhage

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25
Q

old alcoholic with a fall and slow bleed

A

subdural haemorrhage

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26
Q

lucid interval brain haemorrhage due to trauma

A

extradural haemorrhage

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27
Q

young omnivore with psychiatric and then motor symptoms

A

CJD

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28
Q

plaques tau tangles and beta amyloid plaques

A

Alzheimers

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29
Q

alpha synuclein plaques basal ganglia

A

Parkinson’s

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30
Q

optic nerve tumour excised and now has lump on hands

A

NF type 1?

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31
Q

Epileptic patient had patch on back and now lots of lumps in brain

A

Tuberous sclerosis

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32
Q

Mass underneath dura mater compressing parietal lobr

A

Meningioma

33
Q

In adult above the tentorium in the cerebrum brain tumour

34
Q

Capillary loops surrounded by epithelial cells

A

AV malformation

35
Q

Raised ICP symptoms and then loss of consciousness

A

Herniation of brain

36
Q

Thickened pleura in a asbestos exposure worker with FLAWS

A

Mesothelioma

37
Q

farmer with cough SOB clubbing and mouldy hay

38
Q

Amyloidosis affects what lung lobes

39
Q

Pneumoconiosis affects what lung lobes

A

upper lobes

40
Q

smoker with SIADH and FLAWS

A

small cell carcinoma

41
Q

smoker with cancer that has poor prognosis. cells show mucin production

A

squamous cell carcinoma

42
Q

SOB and collapse in a young man

43
Q

Bronchiectasis cause

A

recurrent infections, CF patients get it

44
Q

Asthma lung injury pattern

A

Eosinophilic inflammation, epithelium mucus plugs shed

45
Q

Ship worker with pleural plaques

A

asbestosis

46
Q

A1 anti trypsin deficiency lung injury pattern

47
Q

Red sputum pneumonia

A

Strep pneumoniae

48
Q

testicular tumour that secretes AFP

A

germ cell tumours

49
Q

granulomatous scrotum in man from India

50
Q

lesion on penis excised but returned

A

HPV causing condylomata

51
Q

Painless penile ulcer that has healed but now ulcers in mouth

52
Q

Smoker with FLAWS pancrease disease

A

pancreatic cancer

53
Q

Abdo pain raised amylase

A

Acute pancreatitis

54
Q

Painless jaundice large GB

A

Pancreatic cancer

55
Q

pancreas collection of fluid thick wall fibrous capsule with epithelial cell lining

A

Pseudocyst

56
Q

T1DM first diagnosis most of the times

57
Q

Pancreatitis with anti-IgG deposition suggests…

A

Autoimmune pancreatitis with PBC, IBD, SLE, T1DM

58
Q

Childhood pancreatic tumour

A

Pancreablastoma

59
Q

Pancreatic squamous tumour

A

No such thing, doesn’t exist

60
Q

Pancreatic cancer with fat necrosis and nodules

A

Acinar cell carcinoma

61
Q

Macrocysts on USS pancreatic cancer

A

tail of pancreas

62
Q

Barrett’s oesophagus progresses to

A

squamous cell carcinoma of oesophagus

63
Q

signet ring cells cancer

A

gastric carcinoma

64
Q

CF patient tumour causing intestinal obstruction

65
Q

Patient with pernicious anaemia has gastric ulcer

A

MALT lymphoma

66
Q

Barrett’s oesophagus cell changes

67
Q

Most common colon cancer type

A

Adenocarcinoma

68
Q

FAP what do you see?

A

lots of polyps, cancer by 40

69
Q

Gardner’s syndrome, what do you see?

A

same as FAP, but also bone problems

70
Q

Polyps not associated with increased cancer risk

A

Hamartomatous polyps, juvenile polyposis

71
Q

male with FLAWS concern

A

adenocarcinoma

72
Q

sigmoid volvulus is

A

plevis to diaphragms coffee bean sign

73
Q

caecal volvulus is

A

RLQ to LUQ

74
Q

AA amyloidosis and AL amyloidossis

A

AA in inflammatory. AL in myeloma amyloidosis (anything secondary that causes it)

75
Q

Benign renal tumour well circumscribed epithelial cell wall in tubular or papillary pattern

A

Renal adenoma

76
Q

Oncocytoma

A

Benign, large pink granular cytoplasm with fibrosis in the middle

77
Q

Renal cell carcinoma

A

Mostly clear cell, link to VHL which can mets to lung

78
Q

Papillary renal carcinoma associated with

79
Q

Renal tumour in children

Path Past (8 decks)

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