2016 and 2017 questions I got wrong

Question 1

• Disease that causes Hydrops fetalis if caught in first 20wks

Answer 1

Parvovirus B19

Question 2

• Beta lactam with anti-pseudomonal activity

Answer 2

Pipperacillin

Question 3

• Broad spec, no pseudomonal activity usually given with a beta lactamase inhibitor

Answer 3

Amoxicillin + Clavulanic Acid

Co-amoxiclav

Question 4

• A DNA synthesis inhibitor used to treat Pseudomonal infections but bad against anaerobes

Answer 4

Ciprofloxacin

Question 5

• Lady with discharge, no other symptoms, and causative infection found on wet slide microscopy

Answer 5

Trichomonas Vaginalis

Question 6

Vaccine preventable disease that Develops a grey film over the epiglottis

Answer 6

Diptheria

Question 7

• Maculopapular rash moves from face that can cause encephalitis and pneumonitis

Answer 7

Measles

Question 8

• Carcinoma due to H. Pylori infection

Answer 8

MALToma or gastric lymphoma

Question 9

• Patient with a cancer in their bladder following chronic schistosomiasis

Answer 9

Squamous cell carcinoma

Question 10

• Radiosensitive cancer of the testicle in a young man with a white/smooth appearence? (something like that)

Answer 10

Seminoma

Question 11

• 20 year old with a lytic lesion in the diaphysis of his leg - pain alleviated by aspirin

Answer 11

Osteoid Osteoma

Question 12

Sunburst appearance, Codmans triangle in knee.

Adolescent affected. Histology shows malignant mesenchymal cells

Answer 12

Osteosarcoma

Question 13

Over 40 year old with malignant chondrocytes on histology. Calcification on XR

Answer 13

Chondrosarcoma

Question 14

Under 20 year old affected with long bones and pelvis. XR shows onion skinning of periosteum

Answer 14

Ewings sarcoma

Question 15

30 year old female affected in the knee with lytic lesions shown on XR up to the articular surface, borderline malignancy

Answer 15

Giant Cell tumour

Question 16

Middle aged man affected in head neck region with bony outgrowths on top of normal bone.

Answer 16

Osteoma

Question 17

Cotton wool calfication on hands and feet.

Answer 17

Enchondroma

Question 18

Soap bubble appearance, shepards crook deformity in femur

Answer 18

Fibrous dysplasia

Question 19

• Woman with progressive amnesia who has developed bronchopneumonia

Answer 19

Aspiration Pneumonia

Question 20

• Patient with recurrent pneumococcal infections and meningitis

Answer 20

C7 Deficiency

Question 21

• Used to treat malignant melanoma, involved in T cell checkpoints

Answer 21

Ipilimumab (CTLA4-Ig)

Question 22

• Used to treat Lymphoma and RA

Answer 22

Rituximab (CD20)

Question 23

• Used to prevent transplant rejection, by blocking T cell proliferation and activation

Answer 23

Tacrolimus (Calcineurin Inhibitor)

Question 24

• Used to treat ankylosing spondylitis and NICE recommended if two other anti-inflammatories have failed

Answer 24

Secukinumab (IL17 inhibitor)

Question 25

• In its immature form it is specialised to phagocytose pathogens, and in its mature form it is specialised to present to other cells.

Answer 25

Monocyte or Dendritic cell. Pick any of the two if they come up

Question 26

• Mentioned FAS pathway mutation

Answer 26

Autoimmune Lymphoproliferative Syndrome

Question 27

• Woman with flushed face, problems breathing that has happened multiple times with enlarged liver

Answer 27

Carcinoid Syndrome

Question 28

• 10 year old caucasian who had been on a holiday, presented with low platelets and profound anaemia (6g/dl + oliguria) - anaemic blood film showed ?bite cells, and schistocytes

Answer 28

HUS

Question 29

• Philadelphia 9,22 BCR ABL present, TdT was expressed on cells - 22yr old, 70% blasts! No hepatosplenomegaly. No myelocytes or basophilia.

Answer 29

AML cos its progressed from CML

Question 30

• Philadelphia 9,22 BCR ABL present. Middle aged person - 3% blasts

Answer 30

CML

Question 31

• 10 year old with seizures- Low Ca, High PO4 , High PTH,

Answer 31

Pseudohypoparathyroidism

Question 32

2. Microbiology - Food poisoning question – guy develops foul-smelling diarrhoea and cramping pain 5 days after eating chicken at a barbeque

Answer 32

Campylobacter

Would be Giardia if longer

Question 33

1. Most common type of malignancy in the breast?

Phyllodes tumour
Adenocarcinoma
Intra/Invasive ductal carcinoma
Intra/Invasive lobular carcinoma
Ductal carcinoma in situ
Squamous Cell Carcinoma
Angiosarcoma

Answer 33

Invasive Ductal Carcinoma

Question 34

2. Which/What cancer is also known as non-specific type?

Phyllodes tumour
Adenocarcinoma
Intra/Invasive ductal carcinoma
Intra/Invasive lobular carcinoma
Ductal carcinoma in situ
Squamous Cell Carcinoma
Angiosarcoma

Answer 34

Invasive Ductal Carcinoma

Question 35

3. Which/What cancer is associated with (? the presence of?) E cadherins?

Phyllodes tumour
Adenocarcinoma
Intra/Invasive ductal carcinoma
Intra/Invasive lobular carcinoma
Ductal carcinoma in situ
Squamous Cell Carcinoma
Angiosarcoma

Answer 35

Invasive Ductal Carcinoma

Question 36

4. Cancer which has a high, medium and low stage to it.

Phyllodes tumour
Adenocarcinoma
Intra/Invasive ductal carcinoma
Intra/Invasive lobular carcinoma
Ductal carcinoma in situ
Squamous Cell Carcinoma
Angiosarcoma

Answer 36

DCIS

Question 37

2. Man, ex-smoker, with history of hypertension and MI, has sudden chest pain which radiates to the neck

Acute aortic aneurysm
Rupture of embolus in the popliteal fossa
Multiple cerebral infarcts
Left ventricular embolism/Ventricular rupture
Left ventricular hypertrophy
Descending internal carotid thrombus (LAD???)
Renal (?thrombus) or something like this
Renal artery stenosis
Carotid artery stenosis

Answer 37

Descending internal carotid thrombus