2016 and 2017 questions I got wrong Flashcards
• Disease that causes Hydrops fetalis if caught in first 20wks
Parvovirus B19
• Beta lactam with anti-pseudomonal activity
Pipperacillin
• Broad spec, no pseudomonal activity usually given with a beta lactamase inhibitor
Amoxicillin + Clavulanic Acid
Co-amoxiclav
• A DNA synthesis inhibitor used to treat Pseudomonal infections but bad against anaerobes
Ciprofloxacin
• Lady with discharge, no other symptoms, and causative infection found on wet slide microscopy
Trichomonas Vaginalis
Vaccine preventable disease that Develops a grey film over the epiglottis
Diptheria
• Maculopapular rash moves from face that can cause encephalitis and pneumonitis
Measles
• Carcinoma due to H. Pylori infection
MALToma or gastric lymphoma
• Patient with a cancer in their bladder following chronic schistosomiasis
Squamous cell carcinoma
• Radiosensitive cancer of the testicle in a young man with a white/smooth appearence? (something like that)
Seminoma
• 20 year old with a lytic lesion in the diaphysis of his leg - pain alleviated by aspirin
Osteoid Osteoma
Sunburst appearance, Codmans triangle in knee.
Adolescent affected. Histology shows malignant mesenchymal cells
Osteosarcoma
Over 40 year old with malignant chondrocytes on histology. Calcification on XR
Chondrosarcoma
Under 20 year old affected with long bones and pelvis. XR shows onion skinning of periosteum
Ewings sarcoma
30 year old female affected in the knee with lytic lesions shown on XR up to the articular surface, borderline malignancy
Giant Cell tumour
Middle aged man affected in head neck region with bony outgrowths on top of normal bone.
Osteoma
Cotton wool calfication on hands and feet.
Enchondroma
Soap bubble appearance, shepards crook deformity in femur
Fibrous dysplasia
• Woman with progressive amnesia who has developed bronchopneumonia
Aspiration Pneumonia
• Patient with recurrent pneumococcal infections and meningitis
C7 Deficiency
• Used to treat malignant melanoma, involved in T cell checkpoints
Ipilimumab (CTLA4-Ig)
• Used to treat Lymphoma and RA
Rituximab (CD20)
• Used to prevent transplant rejection, by blocking T cell proliferation and activation
Tacrolimus (Calcineurin Inhibitor)
• Used to treat ankylosing spondylitis and NICE recommended if two other anti-inflammatories have failed
Secukinumab (IL17 inhibitor)
• In its immature form it is specialised to phagocytose pathogens, and in its mature form it is specialised to present to other cells.
Monocyte or Dendritic cell. Pick any of the two if they come up
• Mentioned FAS pathway mutation
Autoimmune Lymphoproliferative Syndrome
• Woman with flushed face, problems breathing that has happened multiple times with enlarged liver
Carcinoid Syndrome
• 10 year old caucasian who had been on a holiday, presented with low platelets and profound anaemia (6g/dl + oliguria) - anaemic blood film showed ?bite cells, and schistocytes
HUS
• Philadelphia 9,22 BCR ABL present, TdT was expressed on cells - 22yr old, 70% blasts! No hepatosplenomegaly. No myelocytes or basophilia.
AML cos its progressed from CML
• Philadelphia 9,22 BCR ABL present. Middle aged person - 3% blasts
CML
• 10 year old with seizures- Low Ca, High PO4 , High PTH,
Pseudohypoparathyroidism
- Microbiology - Food poisoning question – guy develops foul-smelling diarrhoea and cramping pain 5 days after eating chicken at a barbeque
Campylobacter
Would be Giardia if longer
- Most common type of malignancy in the breast?
Phyllodes tumour Adenocarcinoma Intra/Invasive ductal carcinoma Intra/Invasive lobular carcinoma Ductal carcinoma in situ Squamous Cell Carcinoma Angiosarcoma
Invasive Ductal Carcinoma
- Which/What cancer is also known as non-specific type?
Phyllodes tumour Adenocarcinoma Intra/Invasive ductal carcinoma Intra/Invasive lobular carcinoma Ductal carcinoma in situ Squamous Cell Carcinoma Angiosarcoma
Invasive Ductal Carcinoma
- Which/What cancer is associated with (? the presence of?) E cadherins?
Phyllodes tumour Adenocarcinoma Intra/Invasive ductal carcinoma Intra/Invasive lobular carcinoma Ductal carcinoma in situ Squamous Cell Carcinoma Angiosarcoma
Invasive Ductal Carcinoma
- Cancer which has a high, medium and low stage to it.
Phyllodes tumour Adenocarcinoma Intra/Invasive ductal carcinoma Intra/Invasive lobular carcinoma Ductal carcinoma in situ Squamous Cell Carcinoma Angiosarcoma
DCIS
- Man, ex-smoker, with history of hypertension and MI, has sudden chest pain which radiates to the neck
Acute aortic aneurysm
Rupture of embolus in the popliteal fossa
Multiple cerebral infarcts
Left ventricular embolism/Ventricular rupture
Left ventricular hypertrophy
Descending internal carotid thrombus (LAD???)
Renal (?thrombus) or something like this
Renal artery stenosis
Carotid artery stenosis
Descending internal carotid thrombus
