Histopath. general

Question 1

what is your utter default in describing any histopath?

Answer 1

severe, multifocal, subacute, necrotising organitis

Question 2

How do you describe the HISTOLOGICAL lesions? tip - 7 points

Answer 2

1. Organ
2. Location
3. Distrubution
4. CELLS
5. NUMBERS
6. DAMAGE - necrosis, debris..
7. AGENTS

Question 3

How do you give a MD of a histo slide? tip - 5 points

Answer 3

1. Severity
2. Distrubution
3. Chronicity
4. Process
5. Of what (organitis)

Question 4

What are the 4 types of necrosis and what are their characteriistics?

Answer 4

1. coagulative - shape, no organelles
2. liquefactive - areas with lots of lipid, enzymes digest
3. caseous - obliterate architecture, cheesey
4. Fat - focal destruction of fat only. chalky, white, dry

Question 5

what are the 2 types of hyperaemia?

Answer 5

passive - venous

active - arterial

Question 6

how do you describe a tumour histogically?

Answer 6

1. boundarys - discrete, invasice
2. damage - necrosis?
3. size
4. nuclear features
5. give mitotic rate

Question 7

which part of the kidney is most at risk of necrosis?

Answer 7

cortex, glomerulli and PCT

Question 8

how many cells thick should transitional epithelium be?

Answer 8

x5 cells

Question 9

what are the typical signs of pyelonephritis?

Answer 9

fibrosis and scarred indentations, eosinophilic liq in tubules, inflamed transitional epithelium, dilated tubules

Question 10

what is karryolysis

Answer 10

dissolution/fading of nuclei

Question 11

what are pyknotic nuclei?

Answer 11

condensed, shrinked nuclei

Question 12

what are karyorhexic nuclei

Answer 12

fragmenting nuclei