Haematopoeitic system

Question 1

what cells are included under the term ‘myeloid’

Answer 1

BM, blood, mononuclear pcytes

Question 2

what cells are included under the term ‘myeloid’

Answer 2

BM, blood, mononuclear pcytes

Question 3

what cells are included under the term ‘lymphoid’

Answer 3

LNs, spleen, thymus, accessory tissues

Question 4

what is the difference bw lymphoma and leukaemia

Answer 4

lymphoid leukaemia = neoplastic lymphocytes in BM and blood stream
lymphoma = neoplastic lymphocytes in tissue only (eg in Lnn)

Question 5

why type of lymphoma responds best to tx?

Answer 5

B cell

Question 6

what are the signs of lymphoma?

Answer 6

pain free, kg loss, lymphadenopathy, anorexic, exopthalmos (if retrobulbar lnn enlarged), d+ pos

Question 7

what is the most common haematopoeitic tumour in dogs?

Answer 7

canine lymphoma

Question 8

what tumour can FeLV cause?

Question 9

lymphomas can be multicentric, alimentary or thymic. which is generally most common?

Answer 9

multicentric

Question 10

name 3 types of bovine lymphoma

Answer 10

1. enzootic = b cell.
2. BLV = 3% develop lymphoma
3. Sporadic = calf –> leukaemia; juvenile –> thymic; 2yo+ cutaneous forms

Question 11

what breed of pig is predisposed to porcine lymphoma?

Answer 11

lrge white

Question 12

what form of lymphoma do mares get?

Answer 12

subcutaneous

Question 13

name 2 types of plasmacytoma

Answer 13

1. cutaneous - benign

2. extramedullary - aggressive

Question 14

where do plasma cell myelomas develop?

what does it cause

Answer 14

active bone
gelatinous mass replaces bone
pain, hypercalcaemia

Question 15

what are histiocytes?

Answer 15

part of mononuclear pcytic system (eg no PMNs)

Question 16

what are the 3 types of histiocytic proliferations

Answer 16

1. cutaenous - regress
2. reactive - wax and wane
3. sarcoma - malignant tumour of mphages

Question 17

what type of histiocytic sarcoma results in non-regenerative anaemia?

Answer 17

haemophagocytic sarcoma. retain fct.

Question 18

name 3 locations of mast cell tumours

Answer 18

1. cutaneous
2. GIT
3. systemic - cats

Question 19

how do you stain for mast cells?

Answer 19

toludine blue

Question 20

enlarged = lymphadenopathy. What is the difference bw reactive hyperplasia and lymphadenitis?

Answer 20

reactive hyperplasia = immune response to Ag

lymphadenitis = inflam response to infectious agent within the node

Question 21

what agents might cause the LNs to shrink?

Answer 21

chemo, FIV

Question 22

chonic lymphadenopathy leads to ……

Answer 22

fibrosis

a) supperative = strangles, fistulates, onion like
b) granulomatous = nodular (TB) or diffuse (viruses)

Question 23

name two types of tumour ot he thymus and desc the difference

Answer 23

1. thymoma = epithelial cell prolif, slow

2. thymic lymphoma = T cell prolif, young, malignant