Histology - Oral Mucosas & Salivary Glands Flashcards

1
Q

What is the vestibule in the oral cavity?

A

It is a horseshoe-shaped space in between your lips/cheeks and teeth/gums.

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2
Q

Very first part of the digestive system

A

Oral cavity (within the arches of the teeth)

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3
Q

Type of tissue that makes up the skin of the mouth?

A

Epidermis and dermis

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4
Q

What type of tissue makes up the inside of our mouth (oral cavity)?

A

Mucosa

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5
Q

Specific name of the lip border?

A

Vermillion border of the lip

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6
Q

3 types of mucosas of the oral cavity & their embryological tissue origin

A

Masticatory mucosa (ectoderm)
Specialized mucosa (endoderm)
Oral mucosa proper (ectoderm)

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7
Q

Mucosa is made up of…

A

epithelium & lamina propria

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8
Q

Mucosa of the gingiva (gums) and hard palate

A

Masticatory mucosa

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9
Q

Mucosa of the dorsal tongue

A

Specialized mucosa

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10
Q

Mucosa of the lining of the mouth (cheeks, ventral tongue)

A

Oral mucosa proper

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11
Q

What layer lies directly underneath the mucosa?

A

submucosa

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12
Q

Define the submucosa

A
  • Layer immediately beneath the mucosa.
  • Connective tissue containing collagen, minor salivary glands, adipose tissue, blood vessels, lymphatics, adipocytes
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13
Q

Two types of submucosa in the oral cavity and where.

A

Dense: gingiva
Loose: oral/lining mucosa

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14
Q

What type of epithelium makes up the oral cavity?

A

Stratified squamous (non-keratinized)

cells in the top layer are alive, have a nucleus

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15
Q

Gingivitis

A

Inflammation of the gums

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16
Q

The epithelium of of the gums is…

A

para-keratinized (partially keratinized)

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17
Q

What is noticeable about the transition between the vermillion border and vestibule?

A

In the vestibule, the epithelium is marked by protrusions of connective tissue called papillae.

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18
Q

What is the purpose of papillae in the epithelium of the vestible?

A

They bring blood vessels closer to the border of the epithelium (since epithelia are not vascularized) - supply nutrients to the avascular epithelium.

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19
Q

What is the name of the epithelium that runs along the root of the tooth?

A

Junctional epithelium (attaches your gums to your tooth)

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20
Q

Describe how the basal lamina reflects to form the attachment between the epithelium and tooth surface?

A

The external basal lamina reflects to form an internal basal lamina that forms an attachment with the tooth enamel.

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21
Q

The direct interface between the tooth enamel and junctional epithelium is a modified…

A

basal lamina (internal basal lamina)

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22
Q

What purges the crevice between the gingiva and tooth enamel of bacteria?

A

Epithelial cell renewal (between the internal and external basal lamina) with exudate.

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23
Q

What is the name of the crevice between the internal and external basal lamina of the junctional epithelium around teeth?

A

Gingival sulcus

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24
Q

What causes the basal lamina to reflect onto itself and form the external and internal basal lamina?

A

Tooth eruption in early childhood.

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25
Q

The gingiva begins at the…

A

muco-gingival junction

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26
Q

Describe the epithelium of the gingiva

A

Masticatory epithelium, para-keratinized (partially keratinized, cells retain nuclei and some organelles)

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27
Q

The gingiva attaches to the tooth via … epithelium

A

junctional epithelium

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28
Q

Gingiva can be subject to 2 diseases

A
  • gingivitis (inflammation)
  • periodontal disease (periodontitis - more advanced form of infection)
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29
Q

Describe the epithelium of the hard and soft palate

A

Masticatory mucosa, parakeratinized (same as gingiva)

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30
Q

The epithelium of the palate reflects to become…

A

the respiratory epithelium (around the soft elastic palate and uvula)

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31
Q

All of the mouth compartments contain minor…

A

salivary glands

32
Q

Describe the ventral (bottom) tongue lining

A

Oral mucosa proper (like your cheeks)

33
Q

Which tongue mucosa is thicker?
a) ventral
b) dorsal

A

b) dorsal

34
Q

The tongue can be separated into 2 sections…

A

body (anterior 2/3)
base (posterior 1/3)

35
Q

The division between the body and base of the tongue is called…

A

sulcus terminalis

36
Q

What part of the tongue house the tonsils?

A

Base

37
Q

Food can get lodged in tonsils due to the presence of…

A

crypts and pores

38
Q

What is the foramen ceacum?

A

An epithelial invagination at the base of the tongue - embryological remnant from the process of forming the thyroid gland.

39
Q

The thyroglossal duct remnant can fill with liquid and form…

A

thyroglossal fistulas and cysts

40
Q

Name the 2 muscles in the tongue

A

Intrinsic muscle
Extrinsic muscle

41
Q

On the dorsal side of the tongue, there are 4 types of…

A

specialized lingual papillae

42
Q

Minor salivary glands are also called…

A

von Ebner’s glands

43
Q

What is the most abundant type of lingual papillae?

A

Filiform lingual papillae

44
Q

Filiform lingual papillae perceive…

A

tactile sensation

45
Q

Filiform papillae are arranged in… and inclined…

A

arranged in V-shaped rows
inclined posteriorly

46
Q

Are filiform lingual papillae keratinized?

A

They have variable degrees of keratinization. The papillae are keratinized on the sides!

47
Q

What is the shape of filiform lingual papillae?

A

Cup-shaped

48
Q

Fungiform lingual papillae are mostly located at…

A

the tip of the tongue

49
Q

Fungiform papillae contain … at their tip

A

taste bud cells

50
Q

Describe the shape of fungiform papillae

A

The are large and rounded

51
Q

Fungiform papillae comprise of …

A

primary and secondary connective tissue papillae

52
Q

Name the papillae present near the sulcus terminalis

A

Circumvallate lingual papillae

53
Q

Circumvallate papillae form a…

A

lingual “V”

54
Q

Circumvallate are characterized by…

A

crypts with taste buds

55
Q

At the base of the circumvallate crypts are…

A

glands (von Ebner’s) (they secrete saliva and wash out the crypts)

56
Q

Lingual papillae only present in children (4th type)

A

Foliate lingual papillae

57
Q

Where are the foliate lingual papillae located? Describe them.

A

Located on the posterior lateral sides of the tongue.

They form folds and contain taste buds.

58
Q

What are the 4 types on lingual papillae (tongue)

A

Filiform lingual papillae
Fungiform lingual papillae
Circumvallate lingual papillae
Foliate lingual papillae (children only)

59
Q

5 primary taste sensations

A

bitter
sweet
sour
salty
umami

60
Q

Each taste bud specializes in …

A

2 out of 5 tastes

61
Q

Food particles can bind taste buds via…

A

taste pores

62
Q

Name the 4 cell types that make up taste buds

A
  1. Sustentacular supporting cells (contains secretory granules)
  2. Neuroepithelial cells
  3. Intermediate cells
  4. Basal, dividing stem cells
63
Q

Taste buds transduce taste sensations via…

A

sensory afferent nerves

64
Q

At the level of the taste pores, the taste bud cells have …

A

large microvilli with taste receptors and ion channels

65
Q

The medical term for taste loss is…

A

ageusia (or hypogeusia)

66
Q

Potential causes of ageusia (taste loss) (8)

A

aging
pregnancy
menopause
xerostomia (dry mouth)
radiotherapy
chemotherapy
crushed or cut nerves
zinc deficiency

67
Q

Bitter, sweet and umami tastes are detected by what type of receptor?

What about sour?
What about salt?

A

Bitter, sweet, umami: G protein-coupled membrane receptors

Sour: Proton (H+) channels

Salt: Sodium channels

68
Q

Epithelial invaginations are extremely important. Some will eventually form your…

A

teeth
vestibule

69
Q

Glands (in general) derive from epithelium (ectoderm or endoderm) as…

A

invaginations

70
Q

The invagination of a future gland develops a lumen and divides into 2 portions…

A
  1. secretory portion
  2. duct portion
71
Q

What is the difference between exocrine and endocrine glands?

A

Exocrine glands: have ducts, secrete to the surface of exterior compartments, have local effects

Endocrine glands: do not have ducts, secrete to CT and to the blood, have systemic effects

72
Q

Name examples of exocrine and endocrine glands

A

Exocrine: salivary glands, pancreas

Endocrine glands: thryoid, parathyroid, adrenal

73
Q

Exocrine glands mostly secrete…
Endocrine glands mostly secrete…

A

Exocrine glands mostly secrete ENZYMES
Endocrine glands mostly secrete HORMONES

74
Q
A
75
Q
A