Histology of the Male Reproductive Tract Flashcards

1
Q

Label this diagram

A
  • C - Capsule
  • ST - Seminiferous tubule
  • R - Rete testis
  • DE - Efferent ducts
  • H - Head of epididymis
  • B - Body of epididymis
  • T - Tail of epididymis
  • V - Vas deferens
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2
Q

Label this histograph

A
  • L - Leydig cells
  • G - Cells of the germ cell lineage
  • S - Sertoli cells
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3
Q

What does the seminiferous epithelium consist of?

A

Two cell types;

  • Sertoli cells
  • Cells of the germ cell lineage
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4
Q

What do the sertoli cells form?

A

The blood-testis environment

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5
Q

What is the importance of the blood-testis environment?

A

It provides a safe environment for spermatogenesis

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6
Q

Why is it important that there is a safe environment for spermatogenesis?

A

Ensures the integrity of the next generation

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7
Q

Where are cells of the germ cell lineage found in the seminiferous tubules?

A

Embedded in sertoli cells

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8
Q

Where are leydig cells found?

A

Interspersed in connective tissue islands, between (but seperated from) seminiferous tubules

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9
Q

What is the function of Leydig cells?

A

Secrete testosterone

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10
Q

Why are tumours of the testis very important?

A

Because they are a high proportion of tumours seen in early life

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11
Q

What % of testicular neoplasms are germ cell tumours?

A

90-95%

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12
Q

What do seminiferous tubules converge on?

A

Rete testis

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13
Q

How do seminiferous tubules converge onto rete testis?

A

Via tubuli recti

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14
Q

Describe the histological features of the rete testis?

A

Simple cuboidal epithelium

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15
Q

What is the function of the rete testis?

A

Provides exit to the duct system for male germ cells

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16
Q

What does the efferent duct connect?

A

The rete testis with the head of the epididymis

17
Q

What are the histological features of the efferent duct?

A

Characteristic scalloped epithelium

18
Q

Label this histogram of the efferent duct

A
  • C - Cilia
  • M - Myoid cells
19
Q

What contributes to sperm transport in the rete testis?

A

Combined ciliary and myoid contraction

20
Q

What control is myoid contraction in the efferent duct under?

A

Autonomic

21
Q

Why is it important that the efferent duct has mechanisms to aid motility?

A

Transports sperm until they develop independent motility

22
Q

What is the vas deferens?

A

A four layered tube that connects the epididymis to the ejaculatory duct

23
Q

What are the layers of the vas deferens?

A
  • Epithelium
  • 3 layers of smooth muscle
24
Q

What kind of epithelium does the vas deferens have?

A

Psuedostratified columnar

25
Q

What are the layers of smooth muscle in the vas deferens?

A

Longitudinal -> Circular -> Longitudinal

26
Q

What happens to the smooth muscle of the vas deferens during ejaculation?

A

It contracts under autonomic control to propel gametes out of the tract

27
Q

What kind of epithelium does the seminal vesicle have?

A

Secretory epithelium

28
Q

What kind of muscle is found in the seminal vesicle?

A

Smooth muscle layer

29
Q

Under what control is the smooth muscle layer of the seminal vesicle?

A

Autonomic

30
Q

What is the purpose of the smooth muscle layer of the seminal vesicle?

A

Sympathetic innervation enables discharge of contents into duct

31
Q

What are the histological features of the prostate?

A
  • 30-50 tubulo-alveolar glands draining into prostatic urethra
  • Ejaculatory ducts merge with urethra within the prostate
  • Characteristic fibromuscular stroma
32
Q

What are the most common prostatic disorders?

A
  • Benign prostatic hypertrophy
  • Prostatic adenocarcinoma
33
Q

What does prostatic adenocarcinoma give rise to histologically?

A

Loss of normal architecture